Results 191 to 200 of about 1,083,142 (408)

Ethylene‐Activated E3 Ubiquitin Ligase MdEAEL1 Promotes Apple Fruit Softening by Facilitating the Dissociation of Transcriptional Repressor Complexes

open access: yesAdvanced Science, EarlyView.
Ethylene‐activated MdEAEL1 mediates the disassembly of the MdZFP3‐MdTPL4‐MdHDA19 transcriptional repression complex, upregulating the histone acetylation levels in the promoter regions of cell wall degradation‐related genes, consequently promoting softening during storage.
Tong Li   +8 more
wiley   +1 more source

The role of PAF in immunopathology: From immediate hypersensitivity reactions to fungal defense

open access: yesBioFactors, Volume 48, Issue 6, Page 1217-1225, November/December 2022., 2022
Abstract Platelet‐activating factor (PAF, 1‐alkyl‐2‐acetyl‐sn‐glycero‐3‐phosphorylcholine) was discovered when the mechanisms involved in the deposition of immune complex in tissues were being scrutinized in the experimental model of rabbit serum sickness.
Mariano Sánchez Crespo   +2 more
wiley   +1 more source

Enhancing Prime Editing Efficiency Through Modulation of Methylation on the Newly Synthesized DNA Strand and Prolonged Expression

open access: yesAdvanced Science, EarlyView.
Prime editors (PEs) enhance gene editing precision but face repair mechanism limitations. DNA methylation (CpG sites) and de novo methyltransferases (DNMT3A/DNMT3B) boost PE efficiency. We developed an episomal PE system (epiPE) using EBNA1/oriP to sustain expression and methylation.
Xiaosong Han   +15 more
wiley   +1 more source

Differential equations for septic theta functions [PDF]

open access: yesarXiv, 2013
We demonstrate that quotients of septic theta functions appearing in S. Ramanujan's Notebooks and in F. Klein's work satisfy a new coupled system of nonlinear differential equations with interesting symmetric form. This differential system bears a close resemblance to an analogous system for quintic theta functions.
arxiv  

Polymer Brush‐Based Asymmetric Porous Patch with Excellent Anti‐Bacterial and Anti‐Contamination Properties Enables Infectious Abdominal Wall Defect Repair

open access: yesAdvanced Science, EarlyView.
A zwitterionic asymmetric patch is developed via self‐induced phase separation. The cationic layer exhibits anti‐bacterial efficacy and releases pro‐healing factor, while the zwitterionic hydrogel prevents contamination and visceral adhesion. The strong mechanical interlocking of two layers leads to a high and stable burst pressure tolerance.
Zeping Huang   +11 more
wiley   +1 more source

The Comparison of Myocardial Dysfunction in Three Forms of Experimental Septic Shock [PDF]

open access: bronze, 1986
Keith J. Peevy   +4 more
openalex   +1 more source

Functional Materials Targeted Regulation of Gasdermins: From Fundamentals to Functionalities and Applications

open access: yesAdvanced Science, EarlyView.
Targeted regulation of pyroptosis to modulate the immune landscape is a novel design strategy for cancer immunotherapy and anti‐inflammatory treatment. Pyroptosis, as a double‐edged sword, underscores the importance of optimizing the design strategy of functional materials and appropriately activating pyroptosis for the effective treatment of diseases.
Luyao Tian   +5 more
wiley   +1 more source

J‐SUPPORT research policy for oral mucositis associated with cancer treatment

open access: yesCancer Medicine, Volume 11, Issue 24, Page 4816-4829, December 2022., 2022
Abstract Background Oral mucositis is one of the main areas of research in supportive and palliative care of cancer patients. However, the methodology of prospective clinical trials on oral mucositis has not been established, despite its uniqueness.
Tomoya Yokota   +7 more
wiley   +1 more source

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016

open access: yesIntensive Care Medicine, 2017
A. Rhodes   +64 more
semanticscholar   +1 more source

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