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Endotoxin in Septic Shock [PDF]

open access: possibleAnesthesia & Analgesia, 1993
Endotoxin is a lipopolysaccharide located on the outer membrane of gramnegative bacteria. Over the last 60 years, researchers have given endotoxin to animals and human volunteers to induce septic shock and investigated the pathophysiologic events associated with this syndrome [1, 2].
Z. M. N. Quezado   +2 more
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SEPTIC ABORTION AND SEPTIC SHOCK

Clinical Obstetrics and Gynecology, 1970
PIP: Septic shock in obstetric cases is described, and patient management is discussed. Cases of septic abortion complicated by septic shock differ from those resulting from bacterial shock. During the 10 years prior to 1968, Boston City Hospital had a yearly average of 550-600 abortions, and about 26% were septic.
Sumner A. Smith   +1 more
openaire   +3 more sources

The Pathophysiology of Septic Shock

Critical Care Clinics, 2009
Septic shock remains a significant challenge for clinicians. Recent advances in cellular and molecular biology have significantly improved our understanding of its pathogenetic mechanisms. These improvements in understanding should translate to better care and improved outcomes for these patients.
O. Okorie Nduka, Joseph E. Parrillo
openaire   +5 more sources

HYPOTHERMIN IN SEPTIC SHOCK

Survey of Anesthesiology, 1962
Abstract 1. 1. A review of the rationale for the use of hypothermia in infectious shock, especially severe peritonitis, is presented. 2. 2. Experience in the use of hypothermia in eighteen patients with severe peritonitis is presented and discussed. 3. 3. Hypothermia is an adjuvant in the therapy of infectious shock and severe peritonitis,
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Septic Shock (Endotoxic Shock)

Clinical Obstetrics and Gynecology, 1973
PIP: The pathophysiology, clinical aspects, medical, and surgical management of endotoxin shock are reviewed. In the primate, the pathophysiology of endotoxin shock is contributed to by selective vasopasm, disseminated intravascular coagulation, and reduced myocardial response to sympathetic stimuli. Studies in the baboon measured various parameters of
Papineni S. Rao, Denis Cavanagh
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Naloxone in septic shock

Critical Care Medicine, 1983
Naloxone, 0.3 mg/kg of a 10 mg/ml solution, was administered as a single bolus to patients in septic shock if their systolic blood pressure (BP) was less than 100 mm Hg or MAP less than 70 mm Hg with evidence of renal or cerebral hypoperfusion. Patients with chronic or acute (less than 12 h) administration of narcotics were excluded.
William S. Howland   +2 more
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Septic Shock in Pregnancy

Obstetrics & Gynecology, 1997
To evaluate the etiology, management, and maternal and perinatal outcome in patients with septic shock during pregnancy.In 18 patients with septic shock during pregnancy, the criteria for the diagnosis were sepsis-induced hypotension unresponsive to adequate fluid resuscitation and requirement for vasopressors.Causes of shock were pyelonephritis (n = 6)
William C. Mabie   +5 more
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Septic Shock and Corticosteroids

New England Journal of Medicine, 1981
SCOPUS: le.j ; info:eu-repo/semantics ...
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Septic abortion with shock

American Journal of Obstetrics and Gynecology, 1962
Abstract 1. 1. A series of 12 cases of septic abortion with shock due to infection are presented. These occurred in 662 cases of septic abortion seen in Detroit Receiving Hospital in the past 2 years. 2. 2. The early recognition of these cases and the institution of massive antibiotic therapy is of crucial importance, since such therapy is ...
Cheng-Chao Yang   +3 more
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Septic Shock

2023
The body’s response to infection consists of the release of various cytokines and mediators inducing a state of vasoplegia clinically characterized by hypotension, increased heart rate, and decreased cardiac output. The hyperdynamic low-pressure state, which we recognizes in clinical practice, is usually the consequence of the initial fluid ...
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