Results 111 to 120 of about 13,018,603 (325)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Molecular Epidemiology of Infectious Bursal Disease Virus in Mizoram during 2021–2022

International Journal of Bio-Resource and Stress Management
The study was conducted during the tenure period January, 2021–March, 2022 from different regions of Mizoram where outbreaks suspected to be IBDV were screened by agar gel precipitation test (AGPT) for molecular characterization of circulating ...
R. M. Naveen, P. Roychoudhury, P. K. Subudhi, T. K. Dutta, S. S. T. Udaya   +4 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Yeni Nesil Dizileme (YND) Hakkında Bilinenler (Literatür Taraması)

Düzce Tıp Fakültesi Dergisi, 2018
Yeni Nesil Dizileme (YND) yönteminin temeli DNA’nın enzimatik reaksiyonlarla kesilerek çok sayıda DNA parçasıyla bir kütüphane oluşturulması ve kütüphaneyi oluşturan DNA parçalarının çoğaltılmasına dayanmaktadır. OMIM istatistiklerine göre günümüzde 6000’
Mustafa DOĞAN, Recep ERÖZ, Hüseyin YÜCE, Recep ÖZMERDİVENLİ   +3 more
doaj  

Generalized Natural Density DF⁡(Fk) of Fibonacci Word

Vestnik KRAUNC: Fiziko-Matematičeskie Nauki
This paper explores profound generalizations of the Fibonacci sequence, delving into random Fibonacci sequences, k-Fibonacci words, and their combinatorial properties.
Abdullah, D., Hamoud, J.
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Pox-AbDab: the orthopoxvirus antibody database

Frontiers in Immunology
In August 2024, the World Health Organization declared the mpox orthopoxvirus to be a Public Health Emergency of International Concern for the second time in three years, emphasising the need for continued studies into its microbiology and potential ...
Henriette L. Capel, Eric Ji Da Wang, Benjamin H. Williams, Charlotte M. Deane, Matthew I. J. Raybould   +4 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Temporal Aspects of Crime Events: Conceptual Approaches in Expert Analysis

RUDN Journal of Law
The problem of establishing the temporal characteristics of a crime event has been a subject of study in expert practice for over thirty years. Despite this, law enforcement and researchers have yet to reach a consensus on the relationship between ...
Elena A. Logvinets, Natalya P. Katorgina
doaj   +1 more source

Mutations in the P53 Tumor Suppressor Gene in Colorectal Cancer in Taiwan

Kaohsiung Journal of Medical Sciences, 2003
Mutations in the tumor suppressor gene p53 have been reported as occurring prevalently in a wide range of human tumors. Detection of a mutated p53 is thought to provide useful information for the clinical management of colorectal neoplasm. In this study,
Fu-Hsin Chang, Dong-Sheng Tzeng, For-Wey Lung   +2 more
doaj   +1 more source