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Current Opinion in Structural Biology, 2006
Multiple sequence alignments are an essential tool for protein structure and function prediction, phylogeny inference and other common tasks in sequence analysis. Recently developed systems have advanced the state of the art with respect to accuracy, ability to scale to thousands of proteins and flexibility in comparing proteins that do not share the ...
Robert C, Edgar, Serafim, Batzoglou
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Multiple sequence alignments are an essential tool for protein structure and function prediction, phylogeny inference and other common tasks in sequence analysis. Recently developed systems have advanced the state of the art with respect to accuracy, ability to scale to thousands of proteins and flexibility in comparing proteins that do not share the ...
Robert C, Edgar, Serafim, Batzoglou
openaire +2 more sources
T-Coffee: A novel method for fast and accurate multiple sequence alignment.
Journal of Molecular Biology, 2000We describe a new method (T-Coffee) for multiple sequence alignment that provides a dramatic improvement in accuracy with a modest sacrifice in speed as compared to the most commonly used alternatives.
C. Notredame, D. Higgins, J. Heringa
semanticscholar +1 more source
2016
The increasing importance of Next Generation Sequencing (NGS) techniques has highlighted the key role of multiple sequence alignment (MSA) in comparative structure and function analysis of biological sequences. MSA often leads to fundamental biological insight into sequence-structure-function relationships of nucleotide or protein sequence families ...
Bawono, Punto +5 more
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The increasing importance of Next Generation Sequencing (NGS) techniques has highlighted the key role of multiple sequence alignment (MSA) in comparative structure and function analysis of biological sequences. MSA often leads to fundamental biological insight into sequence-structure-function relationships of nucleotide or protein sequence families ...
Bawono, Punto +5 more
openaire +3 more sources
2003
Publisher Summary This chapter discusses various aspects of multiple sequence alignment. Dynamic programming can be generalized to more than two sequences where one finds the multiple alignments with the best score according to the scoring scheme. Gaps are scored according to their length and the number of sequences that they occur in and the method ...
D G, Higgins, W R, Taylor
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Publisher Summary This chapter discusses various aspects of multiple sequence alignment. Dynamic programming can be generalized to more than two sequences where one finds the multiple alignments with the best score according to the scoring scheme. Gaps are scored according to their length and the number of sequences that they occur in and the method ...
D G, Higgins, W R, Taylor
openaire +2 more sources
2008
Multiple sequence alignment (MSA) has assumed a key role in comparative structure and function analysis of biological sequences. It often leads to fundamental biological insight into sequence-structure-function relationships of nucleotide or protein sequence families.
Pirovano, W., Heringa, J.
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Multiple sequence alignment (MSA) has assumed a key role in comparative structure and function analysis of biological sequences. It often leads to fundamental biological insight into sequence-structure-function relationships of nucleotide or protein sequence families.
Pirovano, W., Heringa, J.
openaire +3 more sources
2022
This chapter focuses on comparing sequences using alignment. Sequence alignment is the operation that consists of matching two or more sequences, in order to highlight their similarity, whether it is local or global. If the alignment is given, then computing a score is a relatively simple task.
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This chapter focuses on comparing sequences using alignment. Sequence alignment is the operation that consists of matching two or more sequences, in order to highlight their similarity, whether it is local or global. If the alignment is given, then computing a score is a relatively simple task.
openaire +1 more source
RAPID: A ReRAM Processing in-Memory Architecture for DNA Sequence Alignment
International Symposium on Low Power Electronics and Design, 2019Sequence alignment is a core component of many biological applications. As the advancement in sequencing technologies produces a tremendous amount of data on an hourly basis, this alignment is becoming the critical bottleneck in bioinformatics analysis ...
Saransh Gupta +4 more
semanticscholar +1 more source
Multithreaded Multiple Sequence Alignments
2005 IEEE Engineering in Medicine and Biology 27th Annual Conference, 2005Based on the mixed idea of Progressive alignment and Divide-and-conquer alignment, two different multithreaded multiple sequence alignment programs, depending on how the guide tree(s) would be applied, are implemented for checking the improvements of alignment speed and sensitivity.
Joanne, Bai, Siamak, Rezaei
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Aligning Non-Overlapping Sequences
International Journal of Computer Vision, 2002zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Caspi, Yaron, Irani, Michal
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