Easy triplex: An online tool for predicting the formation of DNA-RNA triple helices. [PDF]
Xian L+9 more
europepmc +1 more source
Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins
With the ultimate goal of understanding the association of toxin‐immunity modules to temperate phages, we characterized toxins from three prophages and examined cross‐protection from immunity proteins. The toxins exhibit adenosine 3′‐pyrophosphokinase activity and are toxic in Escherichia coli.
Eloïse M. Paulet+6 more
wiley +1 more source
Direct single-nucleotide resolution sequencing of DNA 5-methylcytosine using engineered DNA methyltransferase-mediated CMD-seq. [PDF]
Liu W+12 more
europepmc +1 more source
Ca2+‐mediated response to DMSO was investigated in Saccharomyces cerevisiae cells expressing Ca2+‐dependent aequorin. Cell exposure to DMSO induced a cytosolic Ca2+ wave dependent on the integrity of the Cch1/Mid1 channel. Deletion of KCS1 or VIP1 genes encoding the phosphoinositol pyrophosphate (PP‐IP) synthases suppressed the DMSO‐induced Ca2 ...
Larisa Ioana Gogianu+4 more
wiley +1 more source
Chromosome-level genome assembly of the freshwater bivalve Anodonta woodiana. [PDF]
Chen X+5 more
europepmc +1 more source
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran+3 more
wiley +1 more source
DNA metabarcoding analysis revealed a silent prevalence of environmental pathogenic <i>Leptospira</i> in urban area of Okinawa Island, Japan. [PDF]
Sato Y+7 more
europepmc +1 more source
Single-Step Detection of microRNA via the Programmable DNAzyme Probe-Mediated Multiple Signal Recycling. [PDF]
Shi W, Dai L, Chen W, Wen L.
europepmc +1 more source
Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal+8 more
wiley +1 more source
Molecular basis of Streptomyces ECF σShbA factors transcribing principal σHrdB genes. [PDF]
Liu G+5 more
europepmc +1 more source