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Quantitative analysis of DNA-sequencing electrophoresis

Genetic Analysis: Biomolecular Engineering, 1992
At the heart of the DNA-sequencing process is a remarkably selective electrophoretic separation of up to 1000 oligonucleotide fragments, each differing in size by only a single nucleotide unit. A quantitative analysis of this separation is performed in terms of both selectivity and efficiency.
Paul D. Grossman   +2 more
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DNA Sequence Analysis

2009
In this chapter we introduce some of the elementary concepts for analyzing DNA sequences in terms of “words” of length 1 (bases), 2 (base pairs), 3 (triplets, such as codons), restriction sites, etc. The analysis uses some of the basic probability concepts that we have worked with in the previous chapter.
openaire   +2 more sources

Computer analysis of DNA and protein sequences

European Journal of Biochemistry, 1991
Some recent trends in the development of theoretical methods for DNA and protein sequence analysis are reviewed, with particular emphasis on the design of new databases, motif searches, sequence alignment algorithms and applications of neural networks.
openaire   +3 more sources

Computer support of DNA sequence analysis

Computer Programs in Biomedicine, 1981
The paper describes a package of APL-programs suited for the management and the analysis of DNA sequence data. Most of the application programs are related to experimental work in a DNA sequencing laboratory: Search for overlapping DNA fragments to construct complete DNA sequences; search for restriction sites; computing fragment patterns when cutting ...
R Sommer   +3 more
openaire   +3 more sources

Recent Advances in DNA Sequence Analysi

CRC Critical Reviews in Biochemistry, 1975
(1975). Recent Advances in DNA Sequence Analysi. CRC Critical Reviews in Biochemistry: Vol. 2, No. 4, pp. 455-512.
Ray Wu   +3 more
openaire   +3 more sources

Mitochondrial DNA sequence analysis of human skeletal remains: identification of remains from the Vietnam War.

Journal of Forensic Sciences, 1993
Deoxyribonucleic acid (DNA) sequence analysis of the control region of the mitochondrial DNA (mtDNA) genome was used to identify human skeletal remains returned to the United States government by the Vietnamese government in 1984. The postmortem interval
M. Holland   +6 more
semanticscholar   +1 more source

Video analysis of DNA sequence homologs

Analytical Chemistry, 1992
A method for the rapid quantitative analysis of dot blot assays is presented. A video camera, an NTSC compatible frame grabber board, and an AT personal computer are used to read photographic exposures of the assay plate. Image processing and image analysis techniques are used to calculate the orientation of the dot raster and then to compensate for ...
Michael. Ludwig, Robert J. Hartzman
openaire   +3 more sources

The Preferential Mode Analysis of DNA Sequence

Journal of Theoretical Biology, 1997
After reviewing approaches to the nucleotide correlation of DNA sequences the preferential mode analysis method is emphasized and discussed in detail. The preferred modes and poor modes in coding regions, as well as in introns, 5'-caps and 3'-tails are found through the statistical analysis of sequence data of all kinds of species in GenBank.
Liaofu Luo, Fengmin Ji, Fengmin Ji
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Ribosomal DNA sequence analysis reveals new species groupings in the genus Colletotrichum.

, 1994
Sherriff, C., Whelan, M. J., Arnold, G. M., Lafay, J.-F., Brygoo, Y., and Bailey, J. A. 1994. Ribosomal DNA sequence analysis reveals new species groupings in the genus Colletotrichum. Experimental Mycology 18, 121-138.
C. Sherriff   +5 more
semanticscholar   +1 more source

The Analysis of One DNA Sequence

2001
Before any analysis of a DNA sequence can take place it is first necessary to determine the actual sequence itself, at least as accurately as is reasonably possible. Unfortunately, technical considerations make it impossible to sequence very long pieces of DNA all at once.
Gregory R. Grant, Warren J. Ewens
openaire   +2 more sources

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