Molecular characterization and function analysis of the vitellogenin receptor from the cotton bollworm, Helicoverpa armigera (Hubner) (Lepidoptera, Noctuidae) [PDF]
Developing oocytes accumulate plentiful yolk protein during oogenesis through receptor-mediated endocytosis. The vitellogenin receptor (VgR), belonging to the low-density lipoprotein receptor (LDLR) family, regulates the absorption of yolk protein.
Guo, Yuyuan+6 more
core +4 more sources
AlignScape, displaying sequence similarity using self-organizing maps
The current richness of sequence data needs efficient methodologies to display and analyze the complexity of the information in a compact and readable manner.
Isaac Filella-Merce+7 more
doaj +1 more source
Convergent evolution in structural elements of proteins investigated using cross profile analysis
Background Evolutionary relations of similar segments shared by different protein folds remain controversial, even though many examples of such segments have been found. To date, several methods such as those based on the results of structure comparisons,
Tomii Kentaro+2 more
doaj +1 more source
Prediction of bacterial E3 ubiquitin ligase effectors using reduced amino acid peptide fingerprinting [PDF]
Background Although pathogenic Gram-negative bacteria lack their own ubiquitination machinery, they have evolved or acquired virulence effectors that can manipulate the host ubiquitination process through structural and/or functional mimicry of host ...
Jason E. McDermott+5 more
doaj +2 more sources
The PSIPRED Protein Analysis Workbench: 20 years on
The PSIPRED Workbench is a web server offering a range of predictive methods to the bioscience community for 20 years. Here, we present the work we have completed to update the PSIPRED Protein Analysis Workbench and make it ready for the next 20 years ...
Daniel W. A. Buchan, David T. Jones
semanticscholar +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere+5 more
wiley +1 more source
Pairwise alignment incorporating dipeptide covariation
Motivation: Standard algorithms for pairwise protein sequence alignment make the simplifying assumption that amino acid substitutions at neighboring sites are uncorrelated.
Altschul+34 more
core +1 more source
SeqCP: A sequence-based algorithm for searching circularly permuted proteins
Circular permutation (CP) is a protein sequence rearrangement in which the amino- and carboxyl-termini of a protein can be created in different positions along the imaginary circularized sequence.
Chi-Chun Chen+4 more
doaj
Relative evolutionary rate inference in HyPhy with LEISR [PDF]
We introduce LEISR (Likehood Estimation of Individual Site Rates, pronounced “laser”), a tool to infer relative evolutionary rates from protein and nucleotide data, implemented in HyPhy.
Stephanie J. Spielman+1 more
doaj +2 more sources
As the first web server to analyze various biological sequences at sequence level based on machine learning approaches, many powerful predictors in the field of computational biology have been developed with the assistance of the BioSeq-Analysis. However,
B. Liu, Xin Gao, Han Zhang
semanticscholar +1 more source