Results 51 to 60 of about 3,380,352 (277)

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

An Assembly Sequence Planning Method Based on Multiple Optimal Solutions Genetic Algorithm

Mathematics
Assembly sequence planning (ASP) is an indispensable and important step in the intelligent assembly process, and aims to solve the optimal assembly sequence with the shortest assembly time as its optimization goal.
Xin Wan, Kun Liu, Weijian Qiu, Zhenhang Kang   +3 more
doaj   +1 more source

Knowledge-Based Approach to Assembly Sequence Planning

Journal of Algorithms & Computational Technology, 2011
Assembly sequence planning plays a major role in the manufacturing industry. There are still many challenges in the area of assembly planning. One of the significant reasons is the weakness in effective description of assembly knowledge and information ...
Meiping Wu, Vittal Prabhu, Xiaoyu Li
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Effect of Changes in the Sequence of Assembly Operations on Error Rates: A Case Study From the Car Manufacturing Industry

IEEE Access
Human operator-induced assembly errors affect the quality of car manufacturing. Understanding the factors influencing assembly errors is critical for quality improvement.
Carlos Real, Yaniel Torres
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Research of Assembly Sequence Planning of RV-E Reducer

Jixie chuandong, 2019
Taking RV160E reducer as the research object, the assembly sequence of RV-E is studied. The RV160E sub-assembly and the poly-part parts are divided, and the assembly model diagram, assembly association diagram and assembly association matrix are ...
Haiming Zhao, Jinxiong Cai, Biao Fu, Bo Zhao   +3 more
doaj  

Method to obtain hybrid rapid tools with elementary component assembly [PDF]

, 2013
M. Rivette, P. Mognol, J.Y. Hascoet, (2013) "Method to obtain hybrid rapid tools with elementary component assembly", Rapid Prototyping Journal, Vol. 19 Iss: 2, pp.77 - 87 DOI : 10.1108/13552541311302923Purpose – The purpose of this paper is to propose a
MOGNOL, Pascal, HASCOET, Jean-Yves, RIVETTE, Mickaël   +2 more
core   +1 more source