Results 141 to 150 of about 4,751,605 (346)

Biologic: Gene circuits and feedback in an introductory physics sequence for biology and premedical students [PDF]

, 2014
S. B. Cahn, S. G. J. Mochrie
openalex   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

ANNOUNCING COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL: NOT JUST ANOTHER OPEN-ACCESS JOURNAL

Computational and Structural Biotechnology Journal, 2012
Gianni Panagiotou
doaj   +1 more source

DnaSP 6: DNA Sequence Polymorphism Analysis of Large Data Sets.

Molecular biology and evolution, 2017
J. Rozas, Albert Ferrer-Mata, Juan C. Sánchez-DelBarrio, S. Guirao-Rico, P. Librado, S. Ramos-Onsins, A. Sánchez‐Gracia   +6 more
semanticscholar   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

Molecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla, Simone Venz, Ruslan Al‐Ali, Martin Wendlandt, Mandy Radefeldt, Elke Krüger   +5 more
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Cells, shared memory and breaking the PTM code

Molecular Systems Biology, 2012
Pau Creixell, Rune Linding
doaj   +1 more source

Inferences on the evolution of the ascorbic acid synthesis pathway in insects using Phylogenetic Tree Collapser (PTC), a tool for the automated collapsing of phylogenetic trees using taxonomic information

Journal of Integrative Bioinformatics
When inferring the evolution of a gene/gene family, it is advisable to use all available coding sequences (CDS) from as many species genomes as possible in order to infer and date all gene duplications and losses.
Glez-Peña Daniel, López-Fernández Hugo, Duque Pedro, Vieira Cristina P., Vieira Jorge   +4 more
doaj   +1 more source

Protocol for mitochondrial DNA isolation from Macrobrachium rosenbergii and Penaeus monodon using differential centrifugation

STAR Protocols
Summary: The mitochondrial genome (mitogenome) is a vital tool in molecular phylogenetics, evolutionary biology, and population genetics. Here, we present a protocol for extracting mitochondrial DNA from shrimp (Macrobrachium rosenbergii) and prawn ...
Dipta Chandra Pal, Muhammad Manjurul Karim   +1 more
doaj   +1 more source

The whole genome sequence of the Mediterranean fruit fly, Ceratitis capitata (Wiedemann), reveals insights into the biology and adaptive evolution of a highly invasive pest species [PDF]

, 2016
Alexie Papanicolaou, Marc F. Schetelig, Peter Arensburger, Peter W. Atkinson, Joshua B. Benoit, Kostas Bourtzis, Pedro Castañera, John P. Cavanaugh, Hsu Chao, Christopher Childers, Ingrid M. Curril, Huyen Dinh, HarshaVardhan Doddapaneni, Amanda Dolan, Shannon Dugan, Markus Friedrich, Giuliano Gasperi, Scott M. Geib, Γεώργιος Γεωργακίλας, Richard A. Gibbs, Sarah D. Giers, Ludvik M. Gomulski, Miguel González‐Guzmán, Ana Guillem‐Amat, Yi Han, Artemis G. Hatzigeorgiou, Pedro Hernández‐Crespo, Daniel Hughes, Jeffery W. Jones, Dimitra Karagkouni, Panagiota Koskinioti, Sandra L. Lee, Anna R. Malacrida, Mosè Manni, Kostas D. Mathiopoulos, Angela Meccariello, Shwetha C. Murali, Terence D. Murphy, Donna M. Muzny, Georg Oberhofer, Félix Ortego, Maria D. Paraskevopoulou, Monica F. Poelchau, Jiaxin Qu, Martin Reczko, Hugh M. Robertson, Andrew J. Rosendale, Andrew E. Rosselot, Giuseppe Saccone, Marco Salvemini, Grazia Savini, Patrick Schreiner, Francesca Scolari, Paolo Siciliano, Sheina B. Sim, George Tsiamis, Enric Ureña, Ioannis S. Vlachos, John H. Werren, Ernst A. Wimmer, Kim C. Worley, Antigone Zacharopoulou, Stephen Richards, Alfred M. Handler   +63 more
openalex   +1 more source