Results 191 to 200 of about 1,220,765 (311)

Bridging The Chromosome-Centric And Biology And Disease Human Proteome Projects: Accessible And Automated Tools For Interpreting Biological And Pathological Impact Of Protein Sequence Variants Detected Via Proteogenomics

, 2018
Ray Sajulga, Subina Mehta, Praveen Kumar, James E. Johnson, Candace R. Guerrero, Michaël Ryan, Rachel Karchin, Pratik Jagtap, Timothy J. Griffin   +8 more
openalex   +2 more sources

High Levels of Sequence Polymorphism and Linkage Disequilibrium at the Telomere of 12q: Implications for Telomere Biology and Human Evolution [PDF]

, 2000
Duncan M. Baird, Joanna Coleman, Zoë H. Rosser, Nicola J. Royle   +3 more
openalex   +1 more source

From sequence to function: the impact of the genome sequence on Drosophila biology [PDF]

Briefings in Functional Genomics, 2012
openaire   +2 more sources

Unlocking RNA mysteries: Predicting subcellular localizations with AI. [PDF]

Mol Ther Nucleic Acids
Le NQK.
europepmc   +1 more source

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source

Sequence Similarity: An inquiry based and "under the hood" approach for incorporating molecular sequence alignment in introductory undergraduate biology courses

, 2019
Adam J. Kleinschmit, Benita Brink, Steven Roof, Carlos C. Goller, Sabrina D. Robertson   +4 more
openalex   +1 more source

Differential Transcriptional Regulation of Rat Vasopressin Gene Expression by Estrogen Receptor α and β**This work was supported by Public Health Service Grant NS20311 and the Alzheimer’s Disease Research Center of the University of Washington, AG-05136. These sequence data have been submitted to the DNA Database of Japan/European Molecular Biology Laboratory/GenBank databases under accession number AF112362. [PDF]

, 2000
Robert A. Shapiro, Cong Xu, Daniel M. Dorsa   +2 more
openalex   +1 more source

Revolutionizing Molecular cloning: Introducing FastCloneAssist, a Streamlined Python tool for optimizing primer design in restriction & ligation-independent PCR cloning. [PDF]

PLoS One
Singh PK, Donnenberg MS.
europepmc   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

The fate of artificial transgenes in Acanthamoeba castellanii. [PDF]

BMC Genomics
Colp MJ, Blais C, Curtis BA, Archibald JM.   +3 more
europepmc   +1 more source