Results 291 to 300 of about 5,890,604 (383)

Endowing protein language models with structural knowledge. [PDF]

Bioinformatics
Hartout P, Chen D, Pellizzoni P, Oliver C, Borgwardt K.   +4 more
europepmc   +1 more source

PredHSP: Sequence Based Proteome-Wide Heat Shock Protein Prediction and Classification Tool to Unlock the Stress Biology

, 2016
Ravindra Kumar, Bandana Kumari, Manish Kumar   +2 more
openalex   +2 more sources

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

FEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová, Tímea Kurdiová, Daria Barkova, Natália Pálešová, Jana Babulicová, Silvia Tyčiaková, Marta Novotová, Mária Balážová, Miroslav Sabo, Václav Pustka, Jozef Ukropec, Barbara Ukropcová   +11 more
wiley   +1 more source

European Biophysics Journal - Special Issue Celebrating the 70th Anniversary of the Institute of Biophysics, Czech Academy of Sciences. [PDF]

Eur Biophys J
Kovařík A, Hof M, Bártová E.
europepmc   +1 more source

Genomic Tokenizer: Toward a biology-driven tokenization in transformer models for DNA sequences [PDF]

Bell Raj Eapen
openalex   +1 more source

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

FEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao, Yunlong Li, Lihua Chen, Wenshuo Yang, Yong He, Ye Yang, Dengke Yin, Song Tan   +7 more
wiley   +1 more source

Beyond evolution: <i>De novo</i> designed protein toolkit rewriting the rules of synthetic biology. [PDF]

Biosaf Health
Zhang G, Liu C, Li W, Lu J, Li A, Zhu L.
europepmc   +1 more source

Establishment and optimization of the two‐step induction system for generating primordial germ cell‐like cells from chicken embryonic stem cells

FEBS Open Bio, EarlyView.
This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li, XianShuai Xu, GuangZheng Liu, XiaoQian Lv, JiuZhou Song, HongYan Sun, YingJie Niu, QiSheng Zuo, Wei Han, BiChun Li, Kai Jin   +10 more
wiley   +1 more source

Towards molecular evolutionary epigenomics with an expanded nucleotide code involving methylated bases. [PDF]

DNA Res
Yoshida S, Uchiyama I, Fukuyo M, Kato M, Rao DN, Konno M, Fujiwara SI, Azuma T, Kobayashi I, Kishino H.   +9 more
europepmc   +1 more source

Sequence-independent cloning methods for long DNA fragments applied to synthetic biology

, 2017
Nicole Dalonso, M. Savoldi, Paulo Henrique Condeixa de França, Thaila Fernanda dos Reis, Gustavo H. Goldman, Regina Maria Miranda Gern   +5 more
openalex   +1 more source