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C. elegans : Sequence to Biology
Science, 1998This special issue of Science celebrates a landmark in biology: determination of the essentially complete DNA sequence of an animal genome. The animal is a small invertebrate, the nematode (or roundworm) Caenorhabditis elegans , and the sequence consists of about 97 million base pairs of DNA, approximately one-thirtieth the number in the human genome ...
H. Robert Horvitz +3 more
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Making ICT integral to a science lesson sequence: Biology
, 2020Geoffrey Hilton +3 more
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A Unified String Kernel for Biology Sequence
2008In this paper, we introduce a unified String Kernel. Based on this unified string kernel, we construct improved sparse kernel and composite kernel. Using the same target families and the same test and training set splits as in the protein classification experiments from Weston, we do experiments with these new kernels. The results show that our kernels
Guoming Lai, Shengyun Yang, Dehui Yuan
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Sequencing breakthroughs for genomic ecology and evolutionary biology
Molecular Ecology Resources, 2008AbstractTechniques involving whole‐genome sequencing and whole‐population sequencing (metagenomics) are beginning to revolutionize the study of ecology and evolution. This revolution is furthest advanced in the Bacteria and Archaea, and more sequence data are required for genomic ecology to be fully applied to the majority of eukaryotes.
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Supercomputing in molecular biology: applications to sequence analysis
IEEE Engineering in Medicine and Biology Magazine, 1988Genetic data, accumulating at a rapid pace, are ideally suited to computer analysis. These data pose problems of a magnitude that requires supercomputing. The National Cancer Institute of the US National Institutes of Health (NIH) has developed the Advanced Scientific Computing Laboratory to utilize these data for basic research of relevance to cancer ...
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Computer Applications to Molecular Biology: DNA Sequences
2003Computers have become a necessary tool in all laboratories involved in DNA sequence work. There has been a rapid increase in the amount of DNA sequenced, and the most recent issue of the European Molecular Biology Laboratory (EMBL) Nucleotide Sequence Data Library (release 10, 1987) contains almost 10 million base pairs in almost 9000 entries compared ...
Petter Gustafsson, Robert Harr
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TOWARDS AN ENCYCLOPEDIA OF SEQUENCE BIOLOGY
MOLECULAR PHYLOGENETICS, 2018A. Bolshoy
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Nature Methods, 2013
High-throughput sequencing of massive mutant libraries helps researchers catalog determinants of protein stability.
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High-throughput sequencing of massive mutant libraries helps researchers catalog determinants of protein stability.
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The human growth hormone locus: nucleotide sequence, biology, and evolution.
Genomics, 1989E. Chen +5 more
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Yeast Genome Sequencing: Basic Biology, Human Biology, and Biotechnology
2017Whole-genome sequencing of Saccharomyces cerevisiae is one of the milestones of genome research which complemented the understanding in basic biology and expanded the field of yeast biotechnology. It was the first fungus as well as first eukaryote used for reverse genetic experiments, which created consensus among research community to sequence the ...
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