Results 201 to 210 of about 48,165 (247)

PharmVar GeneFocus: CYP1A2—Clinical Impact, Genetic Variation, and Updated Nomenclature

Clinical Pharmacology &Therapeutics, EarlyView.
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human CYP1A2 gene. CYP1A2 plays a crucial role in the biotransformation of several commonly used drugs, including antipsychotics, antidepressants, anxiolytics, and methylxanthines.
Katalin Monostory, Gonzalo Villapalos Garcia, Dora Koller, Solomon Adams, Chad A. Bousman, Evangelia Eirini Tsermpini, Michelle Whirl‐Carrillo, Amy J. Turner, Volker M. Lauschke, Mohamed Nagy, Erin C. Boone, Teri E. Klein, Pablo Zubiaur, Andrea Gaedigk   +13 more
wiley   +1 more source

Stopping Power of Electron Liquid for Slow Quantum Projectiles

Contributions to Plasma Physics, EarlyView.
ABSTRACT We revisit the problem of the deceleration of a charge moving in a medium. In the low‐velocity limit of the projectile, we construct the fully nonlinear (in the charge–target interaction) theory of the stopping power (SP), which goes beyond the classical Ehrenfest dynamics.
Vladimir U. Nazarov, E. K. U. Gross
wiley   +1 more source

ERCC6L2 ensures repair fidelity for staggered-end DNA double-strand breaks. [PDF]

Nat Commun
Aird EJ, Serrano-Benitez A, Siegner SM, Cannavo E, Belotserkovskaya R, Gueorguieva N, Fielden J, Cullot G, Ammann S, Bader AS, Gupta V, Andrieux G, Raab R, Del Rey González M, Cathomen T, Cejka P, Corn JE, Jackson SP.   +17 more
europepmc   +1 more source

Daily Body (Dis‐)Satisfaction and Dietary Restriction in Women Across the Eating Disorder Spectrum

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Body dissatisfaction is a key risk factor in eating disorder development: It is theorized to promote dietary restriction, thereby contributing to symptom onset. Evidence for this pathway primarily comes from cross‐sectional or multi‐wave questionnaire studies in bulimia nervosa (BN) and anorexia nervosa (AN).
Michaela R. Buehler, Ann‐Kathrin Arend, Julia Reichenberger, Jens Blechert   +3 more
wiley   +1 more source

Hurdles to horizontal gene transfer: species-specific effects of synonymous variation and plasmid copy number determine antibiotic resistance phenotype. [PDF]

Microbiology (Reading)
Finnegan M, Rose CJ, Hamet J, Prat B, Bedhomme S.   +4 more
europepmc   +1 more source

Simulating past and future refugia for temperate trees in northern Italy

Ecography, EarlyView.
During the Quaternary, trees responded to the climatic changes of glacial–interglacial cycles with large‐scale range shifts. Over cold glacials, temperate tree species contracted their ranges and survived in areas known as refugia. Several studies point to the Euganean Hills (Colli Euganei), in Veneto, northern Italy, as one of the northernmost ...
Azzurra Pistone, Paul D. Henne, Petra Boltshauser‐ Kaltenrieder, Willy Tinner, Christoph Schwörer   +4 more
wiley   +1 more source

Spatial patterns of tau accumulation across the Alzheimer's disease spectrum. [PDF]

Alzheimers Dement
Fonseca CS, Chao Y, La Joie R, Rabinovici GD, Jagust WJ, Harrison TM, Alzheimer's Disease Neuroimaging Initiative.   +6 more
europepmc   +1 more source

Enhanced Contribution of Biexciton‐Mediated Decay Kinetics in Perovskite Nanocrystals Via Sequential Ultrafast Excitation

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Sequential ultrafast excitation is shown to increase the relative kinetic weighting of biexciton‐mediated decay in CsPbBr3 nanocrystals without increasing the total excitation fluence. By temporally structuring excitation within the exciton lifetime, the early‐time fast decay contribution becomes more pronounced while the fitted fast decay constants ...
Lijie Wang, Renqian Zhou, Malte Oppermann, Xi Zhang, Jianxin Wang, Jun Yin, Osman M. Bakr, Majed Chergui, Omar F. Mohammed   +8 more
wiley   +1 more source

Deep coverage and extended sequence reads obtained with a single archaeal protease expedite de novo protein sequencing by mass spectrometry.

Cell Syst
Pérez Pañeda L, Kadavá T, Shamorkina TM, Schulte D, Pribil P, Heidelberger S, Narlock-Brand AM, Yannone SM, Snijder J, Heck AJR.   +9 more
europepmc   +1 more source

Structure-driven function of plant lncRNAs: conserved RNA architectures in transcriptional and post-transcriptional regulation. [PDF]

RNA Biol
Shen Y, Dong Q, Ding Y, Zhang H.
europepmc   +1 more source