Results 111 to 120 of about 2,885,310 (330)

Approximate Fixed Point Sequences of Nonlinear Semigroups in Metric Spaces [PDF]

, 2014
M. A. Khamsi
openalex   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Some Geometric Properties of Sequence Spaces Involving Lacunary Sequence

Journal of Inequalities and Applications, 2008
We introduce new sequence space involving lacunary sequence connected with Cesaro sequence space and examine some geometric properties of this space equipped with Luxemburg norm.
Vatan Karakaya
doaj   +1 more source

Exploring the Protein Sequence Space with Global Generative Models. [PDF]

Cold Spring Harb Perspect Biol, 2023
Romero-Romero S, Lindner S, Ferruz N.
europepmc   +1 more source

Internal transcribed spacer (ITS) sequence-based characterization of fungal isolates from multiple yogurt facilities—A case study [PDF]

, 2019
Ariel J. Buehler, Rachel L. Evanowski, Martin Wiedmann, N.H. Martin   +3 more
openalex   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Mining for antimicrobial peptides in sequence space. [PDF]

Nat Biomed Eng, 2023
Wan F, de la Fuente-Nunez C.
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Open type quasi-Monte Carlo integration based on Halton sequences in weighted Sobolev spaces [PDF]

, 2014
Peter Hellekalek, Peter Kritzer, Friedrich Pillichshammer   +2 more
openalex   +1 more source

Space Weather with Uncertainty Quantification: A New Sequence of Data-driven Models of the Solar Atmosphere and Inner Heliosphere

, 2023
N. V. Pogorelov, C. N. Arge, J. A. Linker, Lisa Upton, Brian Van Straalen, Ronald M. Caplan, Phillip Colella, Cooper Downs, Christopher Gebhard, Dinesha V. Hegde, C. J. Henney, Shaela Jones-Mecholsky, Tae Kim, Miko M. Stulajter, Talwinder Singh, James Turtle, M. S. Yalim   +16 more
openalex   +1 more source