Results 131 to 140 of about 8,935,685 (345)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

The Semi-Difference Entire Sequence Space cs ∩ d 1 [PDF]

open access: yes, 2020
Let Γ denote the space of all entire sequences. Let Λ denote the space of all analytic sequences. In this paper, we introduce a new class of sequence space, namely, the semi-difference entire sequence space cs ∩ d 1 . It is shown that the intersection of
K Chandrasekhara Rao   +2 more
core  

On the sequence space defined by a sequence of moduli and on the rate-spaces

open access: yesActa et Commentationes Universitatis Tartuensis de Mathematica, 1996
This article contains no abstract.
openaire   +2 more sources

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

On Some Properties of New Paranormed Sequence Space of Nonabsolute Type

open access: yesAbstract and Applied Analysis, 2012
We introduce some new generalized sequence space related to the space ℓ(𝑝). Furthermore we investigate some topological properties as the completeness, the isomorphism, and also we give some inclusion relations between this sequence space and some of the
Vatan Karakaya, Necip Şimşek
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Safe Functional Inference for Uncharacterized Viral Proteins

open access: yes, 2008
The explosive growth in the number of sequenced genomes has created a flood of protein sequences with unknown structure and function. A routine protocol for functional inference on an input query sequence is based on a database search for homologues ...
Yaniv Loewenstein, Michal Linial
core   +1 more source

QTrim : a novel tool for the quality trimming of sequence reads generated using the Roche/454 sequencing platform [PDF]

open access: yes, 2014
Background Many high throughput sequencing (HTS) approaches, such as the Roche/454 platform, produce sequences in which the quality of the sequence (as measured by a Phred-like quality scores) decreases linearly across a sequence read.
Grace P McCormack   +11 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Generalized Difference Sequence Spaces Defined by Orlicz Functions

open access: yes, 2015
[[abstract]]The idea of difference sequence spaces was introduced by Kizmaz [1] and then this subject has been studied and generalized by various mathematicians.
Altin, Y., Bektas, Ç., Subramanian, N.
core  

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