Results 191 to 200 of about 8,935,685 (345)

A Space-Time Spreading Assisted Multicarrier DS-CDMA System using OVSF Codes Employing Adaptive Mode Switching Thresholds and Adaptive Modulation

open access: yes, 2005
The Concept of Space-Time Spreading (STS) assisted, Adaptive Quadrature Amplitude Modulation (AQAM) aidedMC DS-CDMAis introduced. The AQAMmode-switching thresholds are determined using an on-line real-time Bit-Error-Ratio (BER) based learning procedure ...
Wei, H, Yang, L-L., Hanzo, L.
core  

Fine Sampling of Sequence Space for Membrane Protein Structural Biology. [PDF]

open access: yesJ Mol Biol, 2021
Loukeris M   +5 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Mapping the Uncharted Sequence Space: A k-mer Powered, Alignment-Free Journey through Protein Sequence Space

open access: yes
Understanding distances and distribution of protein families in protein sequence space is crucial for both molecular evolution and protein engineering.
Bornberg-Bauer, E. ; https://orcid.org/   +1 more
core  

ON THE SPECTRAL SEQUENCE OF A FIBER SPACE [PDF]

open access: yesProceedings of the National Academy of Sciences, 1955
Hurewicz, Witold, Fadell, Edward
openaire   +3 more sources

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

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