Results 51 to 60 of about 5,621,799 (250)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Some normed binomial difference sequence spaces related to the ℓ p $\ell_{p}$ spaces
Journal of Inequalities and Applications, 2017 The aim of this paper is to introduce the normed binomial sequence spaces b p r , s ( ∇ ) $b^{r,s}_{p}(\nabla)$ by combining the binomial transformation and difference operator, where 1 ≤ p ≤ ∞ $1\leq p\leq\infty$ .
Meimei Song, Jian Meng
doaj +1 more source
Multipliers of Sequence Spaces
Rocky Mountain Journal of Mathematics, 1993 Let \(A = (a_{nk})\) be a triangular nonnegative regular summability matrix. Denote by \(m_ A\) the linear space of sequences \(\{s_ n\}\) such that the \(A\)-transform is bounded. Let \((c_ 0)_ A\) be the closed subspace of sequences \(\{t_ n\}\) which are evaluated to 0 by \(A\). Denote by \(m_ A\) the Banach space \(\widetilde m_ A/(c_ 0)_ A\).
openaire +2 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
J. Lond. Math. Soc., 2018 The aim of this paper is to introduce and investigate a new class of separable Banach spaces modeled after an example of Garling from 1968.
Fernando Albiac +2 more
openaire +2 more sources
Pre main sequence stars as UV sources for the World Space Observatory-UV mission
, 2011 Pre-main sequence stars are bright UV (UV) sources compared with their main sequence analogues. The source of this excess is the high energy processes associated with the physics of accretion/outflow during early stellar evolution.
Sergei A. Lamzin +3 more
core +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
On 2 - normed space valued paranormed null sequence space
Bibechana, 2013 In this paper we introduce and study a new class c0 ( S, α‾ , u‾ , ||. , .|| ) of sequences with values in 2- normed space as a generalization of basic null sequence space c0. We investigate some conditions pertaining to the containment relations of the
Narayan Prasad Pahari
doaj +3 more sources
Factorization of Hausdorff Operators
AxiomsThroughout this study, we will gain a deeper understanding of Hausdorff operators that are commonly used in operator theory. The Hausdorff matrices Gamma, Cesàro, and Hölder are factorized here to derive novel inequalities.
Hadi Roopaei
doaj +1 more source