Results 91 to 100 of about 8,296,713 (306)

Solvability of an infinite system of $ n $-th order differential equations in a paranormed sequence space and its numerical solution

open access: yesAIMS Mathematics
In this paper, we introduce a ball measure of noncompactness in the Banach sequence space $ bv_q $ $ (1\leq q < \infty) $ containing the space $ l_q $.
Hojjatollah Amiri Kayvanloo   +4 more
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Optimal recovery of operators in sequence spaces

open access: yesResearches in Mathematics
In this paper we solve the problem of optimal recovery of the operator $A_\alpha x= (\alpha_1x_1,\alpha_2x_2,\ldots)$ on the class $W^T_q = \{(t_1h_1,t_2h_2,\ldots)\,:\,\|h\|_{\ell_q}\le 1\}$, where $1\le q < \infty$ and $t_1\ge t_2\ge \ldots \ge 0$, and
V.F. Babenko   +2 more
doaj   +1 more source

On the Classical Paranormed Sequence Spaces and Related Duals over the Non-Newtonian Complex Field

open access: yesJournal of Function Spaces, 2015
The studies on sequence spaces were extended by using the notion of associated multiplier sequences. A multiplier sequence can be used to accelerate the convergence of the sequences in some spaces.
Uğur Kadak   +2 more
doaj   +1 more source

Matrix transformations of double convergent sequences with powers [PDF]

open access: yesProceedings of the Estonian Academy of Sciences
In 1967, I. J. Maddox generalized the spaces c0, c, ℓ∞ by adding the powers pk (k ∈ ℕ) in the definitions of the spaces to the terms of elements of sequences (xk). Gökhan and Çolak in 2004–2006 defined the corresponding double sequence spaces
Maria Zeltser, Şeyda Sezgek
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Some Generalized Difference Sequence Spaces Defined by a Sequence of Moduli in n-Normed Spaces

open access: yesJournal of Function Spaces, 2015
We introduce some new generalized difference sequence spaces by means of ideal convergence, infinite matrix, and a sequence of modulus functions over n-normed spaces.
Abdullah Alotaibi   +2 more
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Almost Sequence Spaces Derived by the Domain of the Matrix

open access: yesAbstract and Applied Analysis, 2013
By using , we introduce the sequence spaces , , and of normed space and -space and prove that , and are linearly isomorphic to the sequence spaces , , and , respectively.
Ali Karaisa, Ümıt Karabıyık
doaj   +1 more source

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