Results 111 to 120 of about 2,333,875 (318)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Wide spread of OXA-48-producing Enterobacteriaceae in Algerian hospitals: A four years’ study

Journal of Infection in Developing Countries, 2018
Introduction: The aim of this study was to investigate the presence of carbapenemase-producing Enterobacteriaceae (CPE) in Algerian hospitals and to characterize the molecular types of carbapenemases found.
Nadjet Aggoune, Hassiba Tali Maamar, Farida Assaous, Badia Guettou, Rym Laliam, Nabila Benamrouche, Ali Zerouki, Malek Naim, Kheira Rahal   +8 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Genetic analysis of completely sequenced disease-associated MHC haplotypes identifies shuffling of segments in recent human history

, 2006
The major histocompatibility complex (MHC) is recognised as one of the most important genetic regions in relation to common human disease. Advancement in identification of MHC genes that confer susceptibility to disease requires greater knowledge of ...
John Trowsdale, Wilming, LG, Roberts Anne N, Coggill, P, Laurens G Wilming, Sarah Sims, Trowsdale, J, Atrazhev Alexey M, Palmer, S, Beck Stephan, Todd John A, Jane Rogers, Sawcer, S, Coggill Penny, Ashurst Jennifer L, Trowsdale John, Almeida Jeff, Alexey M Atrazhev, Elliott John F, Beck, S, Sophie Palmer, Hurles Matthew E, Traherne James A, Roberts, AN, Miretti, M, Stewart, CA, de Jong, PJ, Pieter J de Jong, Stephen Sawcer, Hurles, ME, James A Traherne, C Andrew Stewart, de Jong Pieter J., Matthew E Hurles, Horton, R, Penny Coggill, Jennifer L Ashurst, Sims, S, Horton Roger, Stewart C. Andrew, Almeida, J, Ashurst, JL, Carrington Mary, Elliott, JF, C. Andrew Stewart, Stephan Beck, Rogers Jane, Palmer Sophie, Pieter J. de Jong, Carrington, M, Rogers, J, Atrazhev, AM, Roger Horton, Sawcer Stephen, Traherne, JA, Jeff Almeida, Sims Sarah, John A Todd, Marcos M Miretti, Anne N Roberts, Wilming Laurens G, Todd, JA, Mary Carrington, Miretti Marcos M, John F Elliott   +64 more
core   +1 more source

Type-sequences of modules

Journal of Pure and Applied Algebra, 2001
Let \(R\) be a Noetherian complete local domain of dimension \(1\). In the present paper, the authors define the type sequence \([r_1, \dots, r_n]\) of a fractional ideal \(M\) of \(R\), where \(r_1\) is the Cohen-Macaulay type of \(M\), and they investigate its behavior.
ONETO, ANNA, ZATINI, ELSA
openaire   +2 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Application of sequence stratigraphic concepts to the cretaceous Urgonian carbonate platform, southeast France [PDF]

, 1992
Carbonate platforms are increasingly being studied using sequence stratigraphic concepts and models borrowed from the study of siliciclastic shelves in passive margin settings. The direct transposition of the stratigraphic model for a siliciclastic shelf
Hunt, David William
core  

Antimicrobial Resistance of Hypervirulent Klebsiella pneumoniae: Epidemiology, Hypervirulence-Associated Determinants, and Resistance Mechanisms

Frontiers in Cellular and Infection Microbiology, 2017
Klebsiella pneumoniae is one of the most clinically relevant species in immunocompromised individuals responsible for community-acquired and nosocomial infections, including pneumonias, urinary tract infections, bacteremias, and liver abscesses.
Chang-Ro Lee, Jung Hun Lee, Kwang Seung Park, Jeong Ho Jeon, Young Bae Kim, Chang-Jun Cha, Byeong Chul Jeong, Sang Hee Lee   +7 more
doaj   +1 more source

Smarandache Recurrence Type Sequences

, 1997
Eight particular, Smarandache Recurrence Sequences and a Smarandache General-Recurrence Sequence are defmed below and exemplified (found in State Archives, Rm, Valcea, Romania).
openaire   +3 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source