Results 131 to 140 of about 6,337,317 (349)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
A pattern sequence approach to Stern’s sequence
Discrete Mathematics, 2011 Let w be a binary string and let a_w (n) be the number of occurrences of the word w in the binary expansion of n. As usual we let s(n) denote the Stern sequence; that is, s(0)=0, s(1)=1, and for n >= 1, s(2n)=s(n) and s(2n+1)=s(n)+s(n+1). In this note, we show that s(n) = a_1 (n) + \sum_{w in 1 (0+1)*} s([w bar]) a_{w1} (n) where w bar denotes the ...
Michael Coons, Jeffrey O. Shallit
openaire +4 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
nCk sequences and their difference sequences
CoRR, 2015 A nCk sequence is a sequence of n-bit numbers with k bits set. Given such a sequence C, the difference sequence D of C is subject to certain regularities that make it possible to generate D in 2|C| time, and, hence, to generate C in 3|C| time.
openaire +3 more sources
Exceptional Sequences over Graded Cohen-Macaulay Rings [PDF]
, 1999 The concept of exceptional sequences was developed by Gorodentsev and Rudakov in [3] and generalized by Bondal in [1].
Tokuji Araya, Araya, Tokuji
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Study on the most influential parameters in low-power laser generated ultrasound [PDF]
FME Transactions, 2017 The current work studies the influence of the most widely used time-domain techniques for signal to noise ratio (SNR) increase for laser-generated ultrasound (US), employing a low power (150 mW) modulable diode: these methods utilize highly random pseudo-
Vangi Dario +2 more
doaj
Learning a DFT-based sequence with reinforcement learning: a NAO implementation
Paladyn, 2012 The implementation of sequence learning in robotic platforms offers several challenges. Deciding when to stop one action and continue to the next requires a balance between stability of sensory information and, of course, the knowledge about what action ...
Durán Boris, Lee Gauss, Lowe Robert
doaj +1 more source