Results 91 to 100 of about 515,225 (262)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Nonconvexity of the Set of Hypergraph Degree Sequences [PDF]
The Electronic Journal of Combinatorics, 2013 It is well known that the set of possible degree sequences for a simple graph on $n$ vertices is the intersection of a lattice and a convex polytope. We show that the set of possible degree sequences for a simple $k$-uniform hypergraph on $n$ vertices is not the intersection of a lattice and a convex polytope for $k \geq 3$ and $n \geq k+13$.
openaire +3 more sources
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
GenBank2PubMed: bridging viral genomic data and the scientific literature with AI-assisted curation
Scientific ReportsGenBank entries of pathogenetic viral sequences are typically annotated with host species and epidemiological metadata. However, linking these entries to their corresponding published studies remains labor-intensive.
Kaiming Tao +3 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Tauberian conditions for Conull spaces
International Journal of Mathematics and Mathematical Sciences, 1985 The typical Tauberian theorem asserts that a particular summability method cannot map any divergent member of a given set of sequences into a convergent sequence. These sets of sequences are typically defined by an order growth or gap condition.
J. Connor, A. K. Snyder
doaj +1 more source
A Set Of Conjectures On Smarandache Sequences
, 2001 Searching through the Archives of the Arizona State University, I found interesting sequences of numbers and problems related to them. I display some of them, and the readers are welcome to contribute with solutions or ideas.
openaire +3 more sources
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source