Results 81 to 90 of about 28,982 (257)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

On Cluster Points of Sequences via Fuzzy Topology [PDF]

open access: yesSahand Communications in Mathematical Analysis
The notion of fuzzy convergence, a prominent tool in fuzzy analysis, has wide applications in fuzzy inference. The present paper examines the distinctive features of the cluster points of fuzzy sequences in various fuzzy topological spaces.
Jyothis K Mohan   +2 more
doaj   +1 more source

ASAP-SML: An antibody sequence analysis pipeline using statistical testing and machine learning.

open access: yesPLoS Computational Biology, 2020
Antibodies are capable of potently and specifically binding individual antigens and, in some cases, disrupting their functions. The key challenge in generating antibody-based inhibitors is the lack of fundamental information relating sequences of ...
Xinmeng Li   +2 more
doaj   +1 more source

e2g: an interactive web-based server for efficiently mapping large EST and cDNA sets to genomic sequences

open access: yes, 2004
Krüger J, Sczyrba A, Kurtz S, Giegerich R. e2g: an interactive web-based server for efficiently mapping large EST and cDNA sets to genomic sequences. NUCLEIC ACIDS RESEARCH.
Krüger, Jan   +3 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Complex Orthogonal Spreading Sequences Using Mutually Orthagonal Complimentary Sets

open access: yes, 2006
This paper presents a new family of complex spreading sequences designed using mutually orthogonal(MO) complementary sets. Based on the technique described in this paper, the correlation properties of sets of sequences are compared to well-known Walsh ...
Wysocki, Beata J   +7 more
core   +1 more source

On statistically convergent sequences of closed sets [PDF]

open access: yes, 2016
In this paper, we give the definitions of statistical inner and outer limits for sequences of closed sets in metric spaces. We investigate some properties of statistical inner and outer limits.
Talo, Özer   +2 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Curated eutherian third party data gene data sets

open access: yesData in Brief, 2016
The free available eutherian genomic sequence data sets advanced scientific field of genomics. Of note, future revisions of gene data sets were expected, due to incompleteness of public eutherian genomic sequence assemblies and potential genomic sequence
Marko Premzl
doaj   +1 more source

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