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On Cluster Points of Sequences via Fuzzy Topology [PDF]

Sahand Communications in Mathematical Analysis
The notion of fuzzy convergence, a prominent tool in fuzzy analysis, has wide applications in fuzzy inference. The present paper examines the distinctive features of the cluster points of fuzzy sequences in various fuzzy topological spaces.
Jyothis K Mohan, Sheeja T K, Sunny Kuriakose A   +2 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Cesàro Summable Sequence Spaces over the Non-Newtonian Complex Field

Journal of Probability and Statistics, 2016
The spaces ω0p, ωp, and ω∞p can be considered the sets of all sequences that are strongly summable to zero, strongly summable, and bounded, by the Cesàro method of order 1 with index p.
Uğur Kadak
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

ASAP-SML: An antibody sequence analysis pipeline using statistical testing and machine learning.

PLoS Computational Biology, 2020
Antibodies are capable of potently and specifically binding individual antigens and, in some cases, disrupting their functions. The key challenge in generating antibody-based inhibitors is the lack of fundamental information relating sequences of ...
Xinmeng Li, James A Van Deventer, Soha Hassoun   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

An Activity Rule Based Approach to Simulate ADL Sequences

IEEE Access, 2018
The concept of activities of daily living (ADL) has for many years successfully been used in a broad range of health and health care applications. Recent hardware and software developments suggest that the future use of ADL will not only benefit from the
Stein Kristiansen, Thomas P. Plagemann, Vera Goebel   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural properties of limitwise monotonic reducibility of sequences of sets

Учёные записки Казанского университета: Серия Физико-математические науки, 2018
The paper is devoted to the study of limitwise monotonic sets, as well as to the investigation of the main structural properties of limitwise monotonic reducibility (lm-reducibility) between set and sequence of sets.
D.Kh. Zainetdinov
doaj