Results 111 to 120 of about 1,719,091 (311)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Thin fillers in the cubical nerves of omega-categories
It is shown that the cubical nerve of a strict omega-category is a sequence of sets with cubical face operations and distinguished subclasses of thin elements satisfying certain thin filler conditions. It is also shown that a sequence of this type is the
Steiner, Richard
core
Difference systems of sets (DSS) and frequency-hopping sequences (FHS) are two objects with many applications in wireless communication. Zero-difference balanced function (ZDBF) and near zero-difference balanced functions (NZDBF) are two types of ...
Zongxiang Yi, Chunming Tang
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Subgaussian sequences in probability and Fourier analysis
This is a review on subgaussian sequences of random variables, prepared for the Mediterranean Institute for the Mathematical Sciences (MIMS). We first describe the main examples of such sequences.
Pisier, Gilles
core
Invariant Statistical Convergence of Sequences of Sets with respect to a Modulus Function
We introduce and study the concept of invariant convergence for sequences of sets with respect to modulus function f and give some inclusion relations.
Nimet Pancaroglu, Fatih Nuray
doaj +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Lacunary statistical summability of sequences of sets
In this paper we define the WS_θ-analog of the Cauchy criterion for convergence and show that it is equivalent to Wijsman lacunary statistical convergence. Also, Wijsman lacunary statistical convergence is compared to other summability methods which are defined in this paper.
Ulusu, Uğur, Nuray, Fatih
openaire +2 more sources

