Results 201 to 210 of about 1,430,679 (327)
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Diagnostic Prediction with Sequence-of-sets Representation Learning for Clinical Events
, 2020 Tianran Zhang, Muhao Chen, Alex Bui
openalex +2 more sources
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
The current landscape of adaptive immune receptor genomic and repertoire data: OGRDB and VDJbase. [PDF]
Nucleic Acids ResLees WD +11 more
europepmc +1 more source
The independent set sequence of some families of trees [PDF]
, 2017 David Galvin, Justin Hilyard
openalex +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Backbone rigidity encodes universal viscoelastic signatures in biomolecular condensates. [PDF]
Biophys JYang S, Biswas S, Potoyan DA.
europepmc +1 more source