Results 81 to 90 of about 1,430,679 (327)
On Cluster Points of Sequences via Fuzzy Topology [PDF]
The notion of fuzzy convergence, a prominent tool in fuzzy analysis, has wide applications in fuzzy inference. The present paper examines the distinctive features of the cluster points of fuzzy sequences in various fuzzy topological spaces.
Jyothis K Mohan +2 more
doaj +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Curated eutherian third party data gene data sets
The free available eutherian genomic sequence data sets advanced scientific field of genomics. Of note, future revisions of gene data sets were expected, due to incompleteness of public eutherian genomic sequence assemblies and potential genomic sequence
Marko Premzl
doaj +1 more source
Sequence Set Design for a New LFM-PC Hybrid Modulated Radar Signal [PDF]
Shiyi Li +3 more
openalex +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
An Activity Rule Based Approach to Simulate ADL Sequences
The concept of activities of daily living (ADL) has for many years successfully been used in a broad range of health and health care applications. Recent hardware and software developments suggest that the future use of ADL will not only benefit from the
Stein Kristiansen +2 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Structural properties of limitwise monotonic reducibility of sequences of sets
The paper is devoted to the study of limitwise monotonic sets, as well as to the investigation of the main structural properties of limitwise monotonic reducibility (lm-reducibility) between set and sequence of sets.
D.Kh. Zainetdinov
doaj

