Results 141 to 150 of about 1,873,067 (319)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Assessment of High Throughput Sequencing Quality of Host DNA Enriched From Faeces: A Case From Captive Tiger. [PDF]

Mol Ecol Resour
Yang J, Zhang L, Cui L, Xu H, Ma Y, Liu L, Yu M, Mtui EK, Ren X, Chu J, Zou A, Liu D, Zhang L, Li H, Xu Y, Yang S.   +15 more
europepmc   +1 more source

The Economics of Cell-Free DNA Metagenomic Next-Generation Sequencing for Pathogen Detection

Shangxin Yang
openalex   +2 more sources

Faculty Opinions recommendation of Simultaneous Emergence of Multidrug-Resistant Candida auris on 3 Continents Confirmed by Whole-Genome Sequencing and Epidemiological Analyses.

, 2017
Neil M. Ampel
openalex   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Decision letter for "Variant filtering, digenic variants, and other challenges in clinical sequencing: a lesson from fibrillinopathies"

, 2019

openalex   +1 more source

Defining circulating mononuclear cells in heart failure through single-cell RNA sequencing: new insights for an old disease [PDF]

, 2020
Cristina Panico, Marinos Kallikourdis, Gianluigi Condorelli   +2 more
openalex   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

DiNovo enables high-coverage and high-confidence de novo peptide sequencing via mirror proteases and deep learning. [PDF]

Nat Commun
Cao Z, Peng X, Zhang D, Zhou P, Kang L, Chi H, Wu R, Cheng Z, Zhang Y, Dai J, Li Y, Yao L, Li X, He Y, Yang J, Wang H, Xu P, Fu Y.   +17 more
europepmc   +1 more source

Peer Review #2 of "SNARE-CNN: a 2D convolutional neural network architecture to identify SNARE proteins from high-throughput sequencing data (v0.2)"

, 2019

openalex   +1 more source