Results 111 to 120 of about 17,798 (304)

Model predictive control for unprotected left-turn based on sequential convex programming

open access: yesJournal of Automation and Intelligence
In autonomous driving, an unprotected left turn is a highly challenging scenario. It refers to the situation where there is no dedicated traffic signal controlling the left turns; instead, left-turning vehicles rely on the same traffic signal as the ...
Changlong Hao, Yuan Zhang, Yuanqing Xia
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Optimization of Variable Blank Holder Force Trajectory Using Multi-objective Sequential Approximate Optimization

open access: yes, 2014
先進的な加工法として,成形加工中における材料を抑えるブランクホルダー力を適切に調整する可変ブランクホルダー力による加工法がある.この加工法で最も重要なことは,加工過程で材料に発生するしわ・割れを抑制するような可変ブランクホルダー力の最適軌道を設計することである.本研究では,角筒深絞り加工を対象に,しわと割れを目的関数とした多目的最適設計問題を構築し,多目的逐次近似最適化法を用いて可変ブランクホルダー力の最適軌道を求めた.In sheet metal forming, it is important to
北山, 哲士, 13499, 90339698
core   +1 more source

LIGHTWEIGHT OF THE VEHICLE B PILLAR BASED ON SIX SIGMA ROBUST DESIGN UNDER SIDE IMPACT

open access: yesJixie qiangdu, 2016
Robust design is an effective way to improve the reliability of structure and crash safety by considering uncertainty in vehicle design. In the traditional optimization design of vehicle body,due to ignoring of uncertainty factors,such as processing ...
QIU RuiBin   +4 more
doaj  

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

NUBO: A Transparent Python Package for Bayesian Optimization

open access: yesJournal of Statistical Software
NUBO, short for Newcastle University Bayesian Optimisation, is a Bayesian optimization framework for the optimization of expensive-to-evaluate black-box functions, such as physical experiments and computer simulators.
Mike Diessner   +2 more
doaj   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Finding the Optimal Security Policies for Autonomous Cyber Operations With Competitive Reinforcement Learning

open access: yesIEEE Access
Reinforcement Learning (RL) has been responsible for some of the most impressive advances in the field of Artificial Intelligence (AI). Research in competitive RL has shown that multiple agents competing in an adversarial environment can learn ...
Garrett Mcdonald, Li Li, Ranwa Al Mallah
doaj   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

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