Results 51 to 60 of about 524,301 (215)

Iron chelation therapy in transfusion-dependent thalassemia patients: current strategies and future directions [PDF]

, 2015
Antoine N Saliba, Afif R Harb, Ali T Taher Department of Internal Medicine, Division of Hematology/Oncology, American University of Beirut, Beirut, Lebanon Abstract: Transfusional iron overload is a major target in the care of patients with transfusion ...
Taher AT, Saliba AN, Harb AR, Saliba, Antoine N., Taher, Ali T., Harb, Afif R.   +5 more
core   +1 more source

A Critical Call for Mechanistic Investigations of Metal‐Bacteria Interactions

Advanced Materials, EarlyView.
It is well established that the antibacterial properties of metals have tremendous importance for bioengineering applications. What is not as appreciated, however, is the reproducibility crisis in this field's vast literature. In this perspective, we highlight this reproducibility problem, discuss its sources, and suggest solutions towards focused ...
J. Rackwitz, A. Bandyopadhyay, S. Belkin, S. Bose, N. Eliaz, J. L. Gilbert, T. C. Lowe, F. Mücklich, R. J. Turner, C. C. Tasan   +9 more
wiley   +1 more source

Advances in Bio‐Integrated Edge Computing Systems for Smart and Connected Health

Advanced Materials, EarlyView.
This review explores advances in bio‐integrated edge computing for healthcare, focusing on co‐designing computing, sensing, and energy strategies to overcome integration and power challenges for optimized, decentralized operation. ABSTRACT Recent advances in bio‐integrated healthcare technologies have enabled continuous, high‐resolution monitoring and ...
Gyuwon Kim, Seungwon Yoo, Tae Woog Kang, Yunuo Huang, Woon‐Hong Yeo   +4 more
wiley   +1 more source

High-throughput fabrication of monodisperse magnetic PAM-PEG microspheres via high-aspect-ratio droplet microfluidics for efficient and selective his-tagged protein purification

Chemical Engineering Journal Advances
The development of chromatographic media with uniform particle size, high mechanical strength, and specific binding capacity is crucial for efficient protein purification.
Wenyao Li, Xinling Wang, Na Xu, Wenjie Yang, Yushi Chen, Shengnan Luo, Fang Ma, Huiping Chen, Zisen Zhang, Liguo Zhang   +9 more
doaj   +1 more source

Biomass DNA: An Emerging Building Block for Advanced Materials

Advanced Materials, EarlyView.
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley   +1 more source

Chelation-Controlled Reduction:  Stereoselective Formation of syn-1,3-Diols and Synthesis of Compactin and Mevinolin Lactone

, 2016
Chelation-controlled reduction of chiral β-alkoxy ketones containing a competing β‘-oxygen functionality has been investigated. Various syn-1,3-diols were prepared conveniently by reduction of β-alkoxy ketones with LiI/LiAlH4 (syn:anti selectivity up to >
Hui Lei (2642707), Arun K. Ghosh (468637)   +1 more
core   +2 more sources

Modular nanotherapeutics with spatiotemporal precision for phase-specific treatment of intracerebral hemorrhage

Bioactive Materials
Intracerebral hemorrhage (ICH) is a life-threatening neurological disorder characterized by spatiotemporally evolving pathological cascades, necessitating interventions that dynamically adapt to its multiphasic injury progression. Here, we report modular
Wanli Yu, Zhiyu Chen, Bo Wu, Chunfan Zhang, Ying Han, Dewei Zou, Jianxiang Zhang, Nan Wu   +7 more
doaj   +1 more source

Outcomes of chelation therapies.

, 2019
Outcomes of chelation therapies.
Brenda L. Gallie (249953), Nancy F. Olivieri (6407168), Amir Sabouhanian (6407171)   +2 more
core   +1 more source

“Activation‐Resistance Elimination” Regulation by Lanthanide/Transition Metal Ion‐Coordinated Nanostructures Intensifies Cuproptosis and Tumor Immunotherapy

Advanced Materials, EarlyView.
The lanthanide/transition metal ion coordination nanoparticles, La‐Cu@Lap/IWR‐1, with optimized coordination, have been proven to achieve remarkable results in realizing comprehensive tumor cuproptosis through efficient cuproptosis activation and multidimensional resistance elimination, thereby synchronously realizing the synergistic antitumor effects ...
Junrong Wang, Mengqian Xu, Huaping Zhao, Yulin Xie, Guoqing Zhu, Haoze Li, Qianqian Sun, Yong Lei, Chunxia Li   +8 more
wiley   +1 more source

Chelation-Based Stabilization of the Transition Structure in a Lithium Diisopropylamide Mediated Dehydrobromination:  Avoiding the “Universal Ground State” Assumption

, 2016
Dehydrobrominations of (±)-2-exo-bromonorbornane (RBr) by lithium diisopropylamide (LDA) were investigated to determine the roles of aggregation and solvation.
David B. Collum (1308378), Julius F. Remenar (1337781)   +1 more
core   +1 more source