Results 61 to 70 of about 524,301 (215)

A Critical Review on the Evolution of Chitosan‐Based Injectable Hydrogels in Bone Regeneration

Advanced Materials Interfaces, EarlyView.
The graphical illustration depicts hydrogel formulation using chitosan and biocompatible cross‐linkers, major advantages, and incorporation of cells, osteoinductive factors, and therapeutic drugs. Following injection, pH‐responsive gelation enables controlled drug release, promotes cell recruitment and osteogenic differentiation, enhances extracellular
Shivani Santosh Sakhrani, Abu ul Hassan S. Rana, S. Sudheer Khan   +2 more
wiley   +1 more source

Selective production of novel ACE-inhibitory peptides from brewer’s spent grain via two-stage enzymatic hydrolysis and integrated fractionation

Future Foods
Brewer's spent grain represents an underutilized protein source capable of yielding bioactive peptides with potential health benefits, supporting food system sustainability, aligning with an environmental management system, and contributing to ...
Parichat Paksin, Korrawan Sringarm, Pipat Tangjaidee, Wannaporn Klangpetch, Pornchai Rachtanapun, Ekasit Onsaard, Jaksuma Pongsetkul, Saroat Rawdkuen, Young Hoon Jung, Jinhu Tian, Suphat Phongthai   +10 more
doaj   +1 more source

Chelation-Controlled Reduction of α-Methylated 8-Oxabicyclo[3.2.1]oct-6-en-3-ones with Samarium Diiodide. Diastereoselective Preparation of Secondary Alcohols

, 2016
The title reduction has been effected with high stereocontrol using samarium diiodide in the presence of a proton source. It is concluded that chelation of samarium by the ether oxygen of the substrate directs and facilitates the reduction to equatorial ...
Jens Treu (3040827), H. M. R. Hoffmann (2702899)   +1 more
core   +1 more source

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

Phosphate-solubilizing bacteria drive transformation and release of phosphorus in phosphorus-enriched sludge biochar: Efficacy validation and multifaceted mechanisms

Green Carbon
Phosphorus (P) is an essential non-renewable nutrient; however, its inefficient recovery from sewage sludge leads to considerable losses. Although phosphate-solubilizing bacteria (PSB) can convert insoluble P into bioavailable forms, their application is
Sihui Yang, Yifei Wang, Jiayi Yuan, Bing Tian, Xiaolin Xu, Pengfei Cheng, Artem Yurevich Manyakhin, Lina Wei, Jianhua Fan, Xiongfang An   +9 more
doaj   +1 more source

Transfusion and chelation data.

, 2017
Transfusion and chelation data.
Agnes Guerci-Bresler (3812443), Olivier Ernst (3812410), Valentine Brousse (570309), Christian Rose (3812440), Mariane de Montalembert (570310), Hervé Puy (3812419), Jean-Pierre Vannier (1810573), Amandine Baptiste (3812425), Agnès Lahary (3812416), Thibaud Lefebvre (1844338), Aspasia Stamatoullas (3812446), Caroline Elie (78560), Krimo Bouabdallah (3812428), Zoubida Karim (3812434), Marina Cavazzana (3812413), Jean-Antoine Ribeil (3812437), Mohamed Touati (3812422), Emmanuelle Chauzit (3812431), Cécile Dumesnil (3487409)   +18 more
core   +1 more source

Copper‐Driven Epithelial Barrier Disruption: A Novel Mechanism of COPD Acute Exacerbations Mediated by the TNF‐α/ATP7A Axis

Advanced Science, EarlyView.
This study reveals a copper‐driven mechanism of COPD acute exacerbations mediated by the TNF‐α/ATP7A axis. TNF‐α suppresses the copper transporter ATP7A via competitive NF‐κB/CREB1/CBP signaling, resulting in intracellular copper accumulation, mitochondrial oxidative stress, and epithelial barrier disruption.
Xinru Xiao, Yongzhe Hao, Ziqi Ding, Zhipeng Wang, Yujia Shi, Yanhua Huang, Chunjian Qi, Qian Zhang   +7 more
wiley   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

Sequential Irrigation with Heated Sodium Hypochlorite and HEDP: Combining Strong Tissue Dissolution with Continuous Chelation [PDF]

Aim: To evaluate the cleaning efficacy of preheated Sodium Hypochloride, Intracanal heated NaOCl and sequential irrigation using sodium hypochlorite combined with 1-hydroxyethylidene-1,1-diphosphonic acid (HEDP) chelation in smear layer and debris ...
Shreya Mundhada
core   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source