Results 141 to 150 of about 825,885 (311)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Advancing Sequential Manga Colorization for AR Through Data Synthesis

open access: yesIEEE Access
Manga colorization in augmented reality (AR) environments presents unique challenges, particularly when colorizing manga pages captured in photos under various real-world conditions.
Maksim Golyadkin   +2 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Deep Learning for Sequential Data

open access: yes
Deep Learning (DL) ist ein Teilgebiet des maschinellen Lernens (ML), das auf neuronalen Netzen basiert, die auf verschiedenen Abstraktionsebenen lernen und dabei traditionelle ML Methoden in einer Vielzahl von Aufgaben häufig übertreffen. Diese Dissertation untersucht verschiedene Geschäftsaufgaben mit sequenziellen Daten und analysiert die DL Eignung.
openaire   +2 more sources

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Incremental Mining of Across-streams Sequential Patterns in Multiple Data Streams

open access: yes, 2012
Sequential pattern mining is the mining of data sequences for frequent sequential patterns with time sequence, which has a wide application. Data streams are streams of data that arrive at high speed. Due to the limitation of memory capacity and the need
Yang, Shih-yang; Chao, Ching-ming; Chen, Po-zung; Sun, Chu-hao
core   +1 more source

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