Results 121 to 130 of about 825,885 (311)

Maximum likelihood parameter estimation for latent variable models using sequential Monte Carlo [PDF]

open access: yes
We present a sequential Monte Carlo (SMC) method for maximum likelihood (ML) parameter estimation in latent variable models. Standard methods rely on gradient algorithms such as the Expectation- Maximization (EM) algorithm and its Monte Carlo variants.
Davy, Manuel   +2 more
core   +1 more source

Deep learning on multi-view sequential data: a survey. [PDF]

open access: yesArtif Intell Rev, 2023
Xie Z, Yang Y, Zhang Y, Wang J, Du S.
europepmc   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Generalized Net of the Process of Sequential Pattern Mining by Generalized Sequential Pattern Algorithm (GSP)

open access: yes, 2014
In the present paper is constructed a Generalized net model of a process of sequential pattern mining by a generalized sequential pattern algorithm. Sequence pattern mining is a technique used for predictive data mining.
Bureva, V.   +5 more
core   +1 more source

Budget-Constrained Sequential Auctions with Incomplete Information [PDF]

open access: yes
I study a budget-constrained, private-valuation, sealed-bid sequential auction with two incompletely-informed, risk-neutral bidders in which the valuations and income may be non-monotonic functions of a bidder's type.
Carolyn Pitchik
core   +2 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Practical classification accuracy of sequential data using neural networks

open access: yesMachine Learning with Applications
Many existing studies on neural network accuracy utilize datasets that may not always reflect real-world conditions. While it has been demonstrated that accuracy tends to decrease as the number of benign samples increases, this effect has not been ...
Mamoru Mimura
doaj   +1 more source

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