We present the induced 2-tuple linguistic generalized ordered weighted averaging (2-TILGOWA) operator. This new aggregation operator extends previous approaches by using generalized means, order-inducing variables in the reordering of the arguments and ...
Jose M. Merigo Lindahl +1 more
core
Cognitive mechanisms of learning in sequential decision-making under uncertainty: an experimental and theoretical approach. [PDF]
Front Behav NeurosciCecchini G +9 more
europepmc +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Graph-Informed Sequential Decision Making [PDF]
This dissertation studies graph-informed sequential decision making, where graphs enter the bandit problem either as data—actions, contexts, rewards—or as structure that couples decisions, observations and agents. Algorithms that leverage graph priors to
Wu, Shuang
core
Neurophysiological insights into sequential decision-making: exploring the secretary problem through ERPs and TBR dynamics. [PDF]
BMC PsycholMizrahi D, Laufer I, Zuckerman I.
europepmc +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Determinants of cardiovascular disease and sequential decision-making for treatment among women: A Heckman's approach. [PDF]
SSM Popul Health, 2019 Mishra R, Monica.
europepmc +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Neural correlates of home-based intervention effects on value-based sequential decision-making in healthy older adults. [PDF]
Aging BrainKang K +4 more
europepmc +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source