Results 51 to 60 of about 172,559 (244)

Sequential evidence accumulation in decision making [PDF]

Judgment and Decision Making, 2008
Judgments and decisions under uncertainty are frequently linked to a prior sequential search for relevant information. In such cases, the subject has to decide when to stop the search for information.
Daniel Hausmann, Damian Lage
doaj  

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

High-Voltage Overhead Power Line Fault Location Through Sequential Determination of Faulted Section

Technologies
Overhead power lines (OHPLs) represent the backbone of electric power systems and connect generation sources with consumers. The power supply reliability and maintenance costs of power grids largely depend on accurate fault location on OHPLs, as this ...
Aleksandr Kulikov, Anton Loskutov, Pavel Ilyushin, Andrey Kurkin, Anastasia Sluzova   +4 more
doaj   +1 more source

An analysis of optimistic, best-first search for minimax sequential decision making [PDF]

2014 IEEE Symposium on Adaptive Dynamic Programming and Reinforcement Learning (ADPRL), 2014
We consider problems in which a maximizer and a minimizer agent take actions in turn, such as games or optimal control with uncertainty modeled as an opponent. We extend the ideas of optimistic optimization to this setting, obtaining a search algorithm that has been previously considered as the best-first search variant of the B∗ method.
Lucian Busoniu, Remi Munos, Elod Pall
openaire   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Simultaneous or Sequential? Supplier Product Launch Strategy through E-Commerce Channels with Different Models

Journal of Theoretical and Applied Electronic Commerce Research
As the e-commerce landscape diversifies, suppliers are faced with the critical decision of how to effectively launch their products through e-commerce channels with varying business models.
Zhiwen Li, Baojiao Wang, Yeting Wu
doaj   +1 more source