Results 131 to 140 of about 136,209 (296)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Learning Models of Sequential Decision-Making without Complete State Specification using Bayesian Nonparametric Inference and Active Querying [PDF]
, 2018 Learning models of decision-making behavior during sequential tasks is useful across a variety of applications, including human-machine interaction. In this paper, we present an approach to learning such models within Markovian domains based on observing
Shah, Julie A., Unhelkar, Vaibhav V.
core
The effect of apathy and compulsivity on planning and stopping in sequential decision-making. [PDF]
PLoS Biol, 2022 Scholl J +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Sequential Game Model for Urban Emergency Human–Machine Collaborative Decision-Making
Applied SciencesDecision-making algorithms based on big data, artificial intelligence and other technologies are increasingly being applied to urban emergency decision-making, and urban smart emergency response is gradually appearing to be transformed from traditional ...
Shaonan Shan +4 more
doaj +1 more source
Active learning-based multistage sequential decision-making model with application on common bile duct stone evaluation. [PDF]
J Appl Stat, 2023 Tian H, Cohen RZ, Zhang C, Mei Y.
europepmc +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Decision map for spatial decision making in urban planning
, 2005 In this paper, we introduce the concept of decision map and illustrate the way this new concept can be used effectively to support participation in spatial decision making and in urban planning. First, we start by introducing our spatial decision process
Pusceddu, Clara +3 more
core
Patient Selection for Spinal Cord Stimulation in Treatment of Pain: Sequential Decision-Making Model - A Narrative Review. [PDF]
J Pain Res, 2022 Goudman L +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source