Results 151 to 160 of about 49,380 (287)

Exploratory assessment of milk biomarkers during non‑antibiotic treatment in experimental Staphylococcus warneri goat mastitis. [PDF]

open access: yesWorld J Microbiol Biotechnol
Uzoka UH   +7 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

An exploratory sequential research on the the dynamics of individual career

open access: yes, 2019
The field of Career Management is in critical need of integrative and interdisciplinary research into contemporary career phenomena. This exploratory sequential research responded to this call by exploring and testing novel features of individual career ...
Tran, Hang Thi
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Design and Psychometric Evaluation of the Nurses’ Professionalism Questionnaire (NPQ): A Sequential Exploratory Mixed-Method Study

open access: yes
Abstract Background: With advancements in nursing tasks and technologies, the demand for professional nurses has increased, highlighting issues such as the low average of nurses' professional skills and the lack of a reliable tool to assess nurses' professional status.
Sakineh Parastesh   +4 more
openaire   +1 more source

The Meta-Model Approach for Simulation-based Design Optimization.

open access: yes
The design of products and processes makes increasing use of computer simulations for the prediction of its performance. These computer simulations are considerably cheaper than their physical equivalent. Finding the optimal design has therefore become a
Stinstra, E.
core  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Temporal Clustering of Endometrial Cancer and Hyperplasia in HRT Users with Unscheduled Bleeding: A Retrospective NHS Cohort Study. [PDF]

open access: yesCurr Oncol
Abdelaziz MAM   +8 more
europepmc   +1 more source

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