Results 81 to 90 of about 312,413 (279)

The asymmetric exclusion process: Comparison of update procedures

, 1997
The asymmetric exclusion process (ASEP) has attracted a lot of interest not only because its many applications, e.g. in the context of the kinetics of biopolymerization and traffic flow theory, but also because it is a paradigmatic model for ...
Rajewsky, N., Santen, L., Schadschneider, A., Schreckenberg, M.   +3 more
core   +3 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

ANÁLISE POR INJEÇÃO SEQUENCIAL COM DETECÇÃO POR VOLTAMETRIA DE ONDA QUADRADA PARA DETERMINAÇÃO DE As(III) EM AMOSTRAS DE ÁGUAS USANDO ELETRODO DE OURO

Química Nova
A sequential injection method with square wave anodic stripping voltammetry (SI-SWASV) using screen printed and crystalline gold electrode was developed for determination of As(III).
Fernando Henrique do Nascimento, Jorge Cesar Masini   +1 more
doaj   +1 more source

Modelling Electron Spin Accumulation in a Metallic Nanoparticle

, 2008
A model describing spin-polarized current via discrete energy levels of a metallic nanoparticle, which has strongly asymmetric tunnel contacts to two ferromagnetic leads, is presented.
C. E. Malec, D. Davidović, K. Yamane, M. Julliere, Y. G. Wei   +4 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Automatic in situ sensor based on K2S2O8 oxidation method for total phosphorus detection in marine water

Frontiers in Marine Science
Phosphorus is a key indicator for water quality management due to its role in eutrophication. The variety of phosphorus-containing substances necessitates highly sensitive detection of total phosphorus, particularly through automated methods, to ensure ...
Yanmin Zhang, Yanmin Zhang, Shougang Chen, Yan Liu, Yan Liu, Yan Zou, Yan Zou, Yang Wang, Yang Wang, Shuwei Zhang, Shuwei Zhang, Xiangfeng Kong, Xiangfeng Kong, Yang Gao, Yang Gao, Nan Gao, Nan Gao   +16 more
doaj   +1 more source

Cloud point extraction in flow-based systems

Reviews in Analytical Chemistry, 2016
Cloud point extraction is a green alternative for separation and preconcentration, whose advantages are magnified by coupling with flow analysis. This results in fast extractions, with improved precision and lower reagent consumption and waste generation.
Melchert Wanessa R., Rocha Fábio R.P.
doaj   +1 more source

Subspaces with equal closure

, 2003
We take a unifying and new approach toward polynomial and trigonometric approximation in an arbitrary number of variables, resulting in a precise and general ready-to-use tool that anyone can easily apply in new situations of interest. The key idea is to
de Jeu, Marcel
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source