Results 91 to 100 of about 312,970 (308)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Residue feature analysis with empirical mode decomposition for mining spatial sequential patterns from serial remote sensing images

Научно-технический вестник информационных технологий, механики и оптики
An extensive growth of serial remote sensing images paves the way for abundant data intended for the sequential spatial pattern determination in several fields like monitoring of agriculture, development of urban areas, and the vegetative area.
R. A. Preethi, G. Anandharaj
doaj   +1 more source

Efficiently Approximating Top- $k$ Sequential Patterns in Transactional Graphs

IEEE Access, 2019
In real-world networks, an edge (or vertex) may be associated with a transaction database, where each transaction consists of a set of items to describe the attributes or behaviors of the edge (or vertex).
Mingtao Lei, Xi Zhang, Jincui Yang, Binxing Fang   +3 more
doaj   +1 more source

Discovering Travel Spatiotemporal Pattern Based on Sequential Events Similarity

Complexity, 2020
Travel route preferences can strongly interact with the events that happened in networked traveling, and this coevolving phenomena are essential in providing theoretical foundations for travel route recommendation and predicting collective behaviour in ...
Juanjuan Chen, Liying Huang, Chengliang Wang, Nijia Zheng   +3 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Discovering sequential patterns and interrelations among multiple diseases in electronic medical records using cSPADE algorithm

Archives of Public Health
Background The intricate relationships between diseases are characterized by the sequence and temporal intervals of their onset, which are critical for understanding the essence of comorbidity and predicting disease progression.
He Ma, Qianxin Huang, Hong Zhang, Hui Song, Bo Zhang, Ying Liu, Lin Zhang   +6 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Progression to myocardial infarction short-term death based on interval sequential pattern mining. [PDF]

BMC Cardiovasc Disord, 2023
Wu YS, Taniar D, Adhinugraha K, Wang CH, Pai TW.   +4 more
europepmc   +1 more source

An Algorithm for Mining Strong Negative Fuzzy Sequential Patterns

, 2013
Many methods have been proposed for mining fuzzy sequential patterns. However, most of conventional methods only consider the occurrences of fuzzy itemsets in sequences.
Lin, Nancy P.; Hao, Wei-hua, Chen, Hung-jen; Chang, Chung-i; Chueh, Hao-en
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