Results 191 to 200 of about 312,970 (308)

PREDICTING SEQUENTIAL PATTERN CHANGES IN DATA STREAMS

open access: yes, 2014
Data streams are utilized in an increasing number of real-time information technology applications. Unlike traditional datasets, data streams are temporally ordered, fast changing and massive.
Li, I.H., Liao, I.E., Huang, J.Y.
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Trend analysis on sequential pattern

open access: yes, 2010
碩士本論文在探討分析序列型樣其間隔天數的銷售量之趨勢以設計一套推薦系統。經由統計產品銷售紀錄,我們以間隔天數與銷售量可以得到一個波形圖,此波形圖橫軸為間隔天數縱軸為銷售量,經由趨勢偵測可得知波形的起伏並得以瞭解消費者的購買習性,了解什麼時候可以推薦什麼產品給消費者以刺激她們的購買慾望,並期望能減少消費者購買產品之間的間隔天數,相對的亦能夠促使銷售量上升,且針對重點的消費族群和產品做推銷亦能降低成本花費,如此可以提供決策者一個不錯的建議。This study confers on the trend of
王敬順; Wang, Ching-shun
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Multi-pattern time-aware sequential recommendation with data augmentation

open access: yesDianxin kexue
In sequential recommendation systems, explicit user interaction sequences are used as context to infer the user's next possible action. Time-aware sequential recommendation models explore the temporal information within the sequence and consider the ...
LI Jiale, WANG Ruiqin, YU Yang
doaj  

Sequential pattern mining for discovering gene interactions and their contextual information from biomedical texts. [PDF]

open access: yesJ Biomed Semantics, 2015
Cellier P   +7 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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