FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Sequential pattern formation governed by signaling gradients. [PDF]
Phys Biol, 2016 Jörg DJ, Oates AC, Jülicher F.
europepmc +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Evaluation of relationships between onychomycosis and vascular diseases using sequential pattern mining. [PDF]
Sci Rep, 2018 Bang CH +6 more
europepmc +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Detection of Trends of Internet Traffic Using Sequential Patterns
We propose a new method of possible trend detection in the internet traffic by using sequential pattern analysis. The main steps of this method, such as the template pattern discovery in time-series data and pattern comparison and matching for sequential
Lauks, Gunārs, Jeļinskis, Jans
core
Pmspm:a pincer maximal sequential pattern mining algorithm
, 2010 碩士在過去以 Apriori 為基礎的循序樣式探勘方法中，皆單純採用由下而上的方式從長度較短的頻繁樣式成長至較長的候選樣式，一直成長至沒有更長的候選樣式產生為止，因而若需探勘最長頻繁樣式時則必須將所有的頻繁樣式探勘完才可得到(所謂的最長頻繁樣式就是不屬於其它任一頻繁樣式的子樣式稱之)，造成許多不必要的運算。 本研究提出並建構一個優先探勘最長頻繁樣式之演算法PMSPM，結合由下而上以及由上而下兩種方向的探勘方式，進而早一步於由上而下的方向找出大多數的最長頻繁樣式 ...
吳鎮成; Wu, Chen-cheng
core
Applying sequential pattern mining to investigate cerebrovascular health outpatients' re-visit patterns. [PDF]
PeerJ, 2018 Ou-Yang C +4 more
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
An Efficient Incremental Mining Algorithm for Discovering Sequential Pattern in Wireless Sensor Network Environments. [PDF]
Sensors (Basel), 2018 Lyu X, Ma H.
europepmc +1 more source