Results 161 to 170 of about 310,714 (306)

Mining Frequent Max and Closed Sequential Patterns

, 2002
Although frequent sequential pattern mining has an important role in many data mining tasks, however, it often generates a large number of sequential patterns, which reduces its efficiency and effectiveness.
Ramin Afshar, Dr. Martin Ester, Simon Fraser University   +2 more
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Mapping Background Variables With Sequential Patterns in Problem-Solving Environments: An Investigation of United States Adults' Employment Status in PIAAC. [PDF]

Front Psychol, 2019
Liao D, He Q, Jiao H.
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Mining Maximal Sequential Patterns in Protein Databases

, 2007
蛋白質序列中的序列樣式，和蛋白質所執行的功能有著密不可分的關係。因此，如何從蛋白質序列資料庫中，透過系統化的方法，探勘出重要的序列樣式，已成為一個相當重要的研究課題。 針對此一課題，本論文提出了一個以字尾樹(suffix tree)為基礎的演算法。演算法中的所有過程，包括探勘序列樣式中的封閉性高頻子字串(closed frequent substring)，將封閉性子字串組成最大高頻序列樣式(maximal frequent sequential pattern)，以及調整序列樣式中子字串間的間隔 ...
凌宇, Ling, Yu
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Sequential patterns of spikes and scale-invariance in modular networks [PDF]

BMC Neurosci, 2014
Leleu T, Aihara K.
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Discovering sequential patterns and interrelations among multiple diseases in electronic medical records using cSPADE algorithm. [PDF]

Arch Public Health
Ma H, Huang Q, Zhang H, Song H, Zhang B, Liu Y, Zhang L.   +6 more
europepmc   +1 more source

Exclusive Sequential Patterns and their Graphical Representation

, 2011
This paper builds on a novel approach to sequential patterns post-processing, where a corresponding data mining method was proposed recently for discovery of Exclusive Sequential Patterns (ESP). A graphical model is introduced as an extension of previous
Lu, Jing
core