Results 51 to 60 of about 26,362,948 (329)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Journal of Intensive Care, 2020 Background Acute respiratory distress syndrome (ARDS) is a common and disabling disease with high rates of mortality and morbidity. The role of steroids in treating ARDS remains controversial.
Yazan Zayed +12 more
semanticscholar +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Sequential analysis and its applications to neuromorphic engineering
Frontiers in NeuroscienceIntroduction:Neuromorphic circuits operate by comparing fluctuating signals to thresholds. This operation underpins sensing and computation in both neuromorphic architectures and biological nervous systems.
Shivaram Mani, Saeed Afshar, Travis Monk
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Development of cost functions for wastewater treatment by sequential batch reactor
Journal of Environmental Engineering and Landscape ManagementSequential batch reactor is widely used for industrial wastewater treatment. To consider sequential batch reactor for biological treatment of wastewater at a specific site, it is essential to ensure economy and sustainability.
Bhaskar Sengupta +2 more
doaj +1 more source
Focus on Data: Statistical Design of Experiments and Sample Size Selection Using Power Analysis
Investigative Ophthalmology and Visual Science, 2020 Purpose To provide information to visual scientists on how to optimally design experiments and how to select an appropriate sample size, which is often referred to as a power analysis. Methods Statistical guidelines are provided outlining good principles
J. Ledolter, R. Kardon
semanticscholar +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
On optimality of kernels for approximate Bayesian computation using sequential Monte Carlo [PDF]
, 2011 Approximate Bayesian computation (ABC) has gained popularity over the past few years for the analysis of complex models arising in population genetics, epidemiology and system biology.
Barnes, C +7 more
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