Results 71 to 80 of about 26,362,948 (329)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

LISA: Virginia Tech's Laboratory for Interdisciplinary Statistical Analysis Annual Report 2014-15

open access: yes, 2016
The 2014-15 academic year was very successful for LISA, Virginia Tech’s Laboratory for Interdisciplinary Statistical Analysis. LISA statistical collaborators helped 1349 researchers around Virginia Tech for the three main services of Collaboration ...
Vance, Eric A., Pruitt, Tonya
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Virginia Tech's Laboratory for Interdisciplinary Statistical Analysis Annual Report 2015-16

open access: yes, 2016
This annual report summarizes the activities of LISA, Virginia Tech’s Laboratory for Interdisciplinary Statistical Analysis, during the fall and spring semesters of the 2015-16 academic year.
Vance, Eric A., Pruitt, Tonya
core  

Sequential stopping for high-throughput experiments [PDF]

open access: yes, 2013
In high-throughput experiments, the sample size is typically chosen informally. Most formal sample-size calculations depend critically on prior knowledge.
Müller, Peter, Rossell, David
core   +1 more source

Kansas highway and traffic statistics, 1980, with 1979 appendix. Highway and traffic statistics, 1980, with 1979 appendix.

open access: yes, 1982
This report was issued by: Governor's Committee on Criminal Administration, Statistical Analysis Center. Reports for 1982-1986 were issued by the Kansas Bureau of Investigation, Statistical Analysis Center."The following report presents highway and ...
Kansas. Governor's Committee on Criminal Administration. Statistical Analysis Center.
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Factors associated with farmers’ well-being in meaningful environments: a chain psychological association of digital literacy, psychological empowerment, and farmers’ decision-making behaviors

open access: yesFrontiers in Psychology
IntroductionThe formation of farmers’ well-being is closely related to digital literacy, psychological empowerment, and agricultural planting decision-making behavior.
Meng Luo
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

The efficacy and safety of addition of pegylated interferon to long-term nucleos(t)ide analogue therapy on functional cure of chronic hepatitis B patient: a systematic review and meta-analysis

open access: yesFrontiers in Pharmacology
ObjectiveThis meta-analysis aims to assess the efficacy and safety of adding pegylated interferon (Peg-IFN) to long-term nucleos(t)ide analogs (NAs) treatment for achieving functional cure in patients with chronic hepatitis B (CHB).MethodsThis meta ...
Xu Zhang   +5 more
doaj   +1 more source

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