Results 111 to 120 of about 268,793 (310)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Croatian Journal of Food Science and Technology, 2011 A sequential optimization based on experimental design method was employed to optimize the concentration of media components for improvement of citric acid production from paddy straw by solid state fermentation using Aspergillus niger.
M. M. D. Zulkali, Hayder Kh. Q. Ali
doaj
Nursing OpenAim To provide a comprehensive understanding of how nurse managers' leadership styles affect staff engagement and to identify key themes that influence engagement from both statistical and experiential perspectives within a multicultural healthcare ...
Amal Alluhaybi +3 more
doaj +1 more source
Academician V.S. Mikhalevich and His Department
Кібернетика та комп'ютерні технологіїMarch 10 marked the 95th anniversary of the birth of the outstanding scientist and associate of Viktor Mikhailovich Glushkov, Academician Volodymyr Serhiyovych Mikhalevich.
Vasyl Biletskiy +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Design and Analysis of Monte Carlo Experiments [PDF]
monte carlo experiments;simulation models;mathematical analysis;sensitivity analysis;experimental ...
Kleijnen, J.P.C.
core +1 more source
Journal of Manufacturing and Materials ProcessingThe directed energy deposition (DED) parameters were determined for near-β alloy Ti-55511 by employing statistical design of experiments (DOEs) methods.
Addison J. Rayner +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Optimal Selection of Building Components Using Sequential Design via Statistical Surrogate Models [PDF]
, 2020 Choosing the optimal combination of building components that minimize investment and operational costs is a topic of great importance in the building simulation community.
Rui Zhang +5 more
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