Results 81 to 90 of about 5,820 (141)

Exiting the erythrocyte: functional and temporal analysis of a malarial subtilase [PDF]

, 2010
Plasmodium falciparum is an obligate intracellular parasite, which causes 95% of worldwide malaria cases annually. Malarial symptoms occur during replication of parasites inside erythrocytes. Multiple cycles of host cell invasion, replication inside a
Silmon de Monerri, N.C.
core  

Dissecting EXP2 sequence requirements for protein export in malaria parasites. [PDF]

Front Cell Infect Microbiol, 2023
Pitman EL, Counihan NA, Modak JK, Chowdury M, Gilson PR, Webb CT, de Koning-Ward TF.   +6 more
europepmc   +1 more source

A protease cascade regulates egress of Plasmodium falciparum from the human erythrocyte [PDF]

, 2018
Malaria parasites invade erythrocytes and replicate inside a parasitophorous vacuole (PV). Invasive merozoites eventually egress in a process that involves sequential rupture of first the PV membrane (PVM) then the erythrocyte membrane.
Thomas, James A
core  

Chemical Genetic Approaches for Elucidating Protease Function and Drug-Target Potential in Plasmodium Falciparum [PDF]

, 2012
Plasmodium falciparum is a protozoan parasite and the causative agent of malaria, which kills upwards of 1 million people annually. With the increasing prevalence of drug-resistant parasites, considerable interest now exists in the identification of new ...
Harbut, Michael
core   +1 more source

Homing in on getting out: characterisation of SERA6, a putative malarial protease with a role in egress [PDF]

, 2012
The human malaria parasite, P. falciparum, replicates within a membrane-bound intraerythrocytic parasitophorous vacuole (PV). The resulting daughter merozoites actively escape from the host cell in a process called egress.
Ruecker, A.
core  

Activation loop phosphorylation and cGMP saturation of PKG regulate egress of malaria parasites. [PDF]

PLoS Pathog
Koussis K, Haase S, Withers-Martinez C, Flynn HR, Kunzelmann S, Christodoulou E, Ibrahim F, Skehel M, Baker DA, Blackman MJ.   +9 more
europepmc   +2 more sources

Faculty Opinions recommendation of Plasmodium pseudo-Tyrosine Kinase-like binds PP1 and SERA5 and is exported to host erythrocytes.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2019
Toshihiro Horii, Nirianne Palacpac
openaire   +2 more sources

Mechanisms of PfDNMT2 inhibition and PfATP6-mediated resistance to the antimalarial candidate SC83288 in Plasmodium falciparum. [PDF]

Nat Commun
Sanchez CP, Duffey M, Celada RV, Kucharski M, Hoarau M, Saeyang T, Kamchonwongpaisan S, Sohraby F, de Buhr S, Nunes Alves A, Lucky AB, Miao J, Regnault C, Dziekan JM, Bozdech Z, Barrett MP, Lanzer M.   +16 more
europepmc   +1 more source

MK-7602: a potent multi-stage dual-targeting antimalarial. [PDF]

EBioMedicine
Favuzza P, Palandri J, de Lera Ruiz M, Bailey W, Boyce CW, Danziger A, Fawaz MV, Kelly M, Murgolo N, Robbins JA, Vavrek M, Zhao L, Lei Z, Guo Z, Reaksudsan K, Steel RWJ, Hodder AN, Ngo A, Dziekan JM, Thompson JK, Triglia T, Birkinshaw RW, Penington JS, Scally SW, Dans MG, Coyle R, Sevilleno N, Orban A, Feufack-Donfack LB, Popovici J, Lee MCS, Papenfuss A, Lowes KN, Sleebs BE, McCarthy JS, McCauley JA, Boddey JA, Olsen DB, Cowman AF.   +38 more
europepmc   +1 more source

Age-dependent carriage of alleles and haplotypes of Plasmodium falciparum sera5, eba-175, and csp in a region of intense malaria transmission in Uganda [PDF]

International Journal of Infectious Diseases, 2016
openaire   +1 more source