Results 231 to 240 of about 10,338 (254)
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European Journal of Histochemistry
Heart failure with preserved ejection fraction (HFpEF), a complex disease that is increasingly prevalent due to population aging, pose significant challenges in its treatment.
Jinshuang Li +6 more
semanticscholar +1 more source
Heart failure with preserved ejection fraction (HFpEF), a complex disease that is increasingly prevalent due to population aging, pose significant challenges in its treatment.
Jinshuang Li +6 more
semanticscholar +1 more source
Circulation, 2022
Introduction: Despite advances in cardioprotection, new therapeutic strategies capable of preventing acute myocardial ischemia-reperfusion injury and reducing secondary event of patients are still needed.
Fabrice Gonnot +18 more
semanticscholar +1 more source
Introduction: Despite advances in cardioprotection, new therapeutic strategies capable of preventing acute myocardial ischemia-reperfusion injury and reducing secondary event of patients are still needed.
Fabrice Gonnot +18 more
semanticscholar +1 more source
Oligomerization of the Sarcoplasmic Reticulum Ca2+-ATPase SERCA2 in Cardiac Muscle
Molecular Cell Biology Research Communications, 1999The slow/cardiac isoform of the sarcoplasmic reticulum Ca2+-ATPase plays an important role in cardiac muscle Ca2+-homeostasis. To determine the native configuration of the SERCA2 ion pump, a chemical cross-linking analysis of heart microsomes was performed.
N J, Lennon +3 more
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The SERCA2: A Gatekeeper of Neuronal Calcium Homeostasis in the Brain
Cellular and Molecular Neurobiology, 2018Calcium (Ca2+) ions are prominent cell signaling regulators that carry information for a variety of cellular processes and are critical for neuronal survival and function. Furthermore, Ca2+ acts as a prominent second messenger that modulates divergent intracellular cascades in the nerve cells.
Aikaterini, Britzolaki +4 more
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Nitrotyrosine-modified SERCA2: a cellular sensor of reactive nitrogen species
Pflügers Archiv - European Journal of Physiology, 2008The endo-/sarcoplasmic reticulum Ca(2+)-Mg(2+)-adenosine triphosphatase (SERCA2) isoform of the sarco/endoplasmic reticulum Ca(2+)-ATPase is sensitive to cellular conditions of inflammation and oxidative stress as evidenced by the common appearance of 3-nitrotyrosine-modified forms of SERCA2 in aging and disease in both striated and smooth muscle of ...
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The SERCA2 gene: genomic organization and promoter characterization
2003The sarco(endo)plasmic reticulum Ca2+-ATPases belong to a family of active calcium transport enzymes encoded by SERCA1, 2 and 3 genes. In this study, we describe the complete structure of the human SERCA2 gene and its 5′-regulatory region. The hSERCA2 gene is located in chromosome 12 position q24.1 in Contig NT_009770.8, spans 70 kb and is organized in
Angel Zarain-Herzberg +1 more
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Identification of a new SERCA2 splice variant regulated during monocytic differentiation
Biochemical and Biophysical Research Communications, 2003Sarco/endoplasmic reticulum-type calcium transport ATPases (SERCA enzymes) pump calcium ions from the cytosol into the endoplasmic reticulum. We report that in addition to the ubiquitously expressed SERCA2b isoform, a new splice variant of SERCA2 can be detected (SERCA2c) that arises from the inclusion of a short intronic sequence located between exons
Pascal, Gélébart +3 more
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Mitochondrial transcription factors regulate SERCA2 gene transcription
Journal of Molecular and Cellular Cardiology, 2006A WATANABE +5 more
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