Results 111 to 120 of about 88,119 (330)
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
La « mise en pièce » de Renée : Genèse et impératifs de l’adaptation d’Émile Zola
Usually known due to his journalistic commitment and his famous novels, Emile Zola succumbs to the « theatrical temptation » described by Philippe Chardin.
Nejma Omari
doaj +1 more source
The dawn of the copy in the Bronze Age
Contemporary everyday life is dominated by industrially reproduced serial objects that we perceive as easily replaceable in case of dam- age or loss. We are used to seriality, i.e.
Forberg, C., Stockhammer, P.
core
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Quality assessment of automatically planned O-Ring linac SBRT plans for pelvic lymph node metastases, finding the optimal minimum target size by comparison with robotic SBRT. [PDF]
Hernández KVD +2 more
europepmc +1 more source
Обоснование и выбор метода калькуляции себестоимости продукции в зависимости от типа производства и длительности производственного цикла [PDF]
In the junk different methods of the formation of the prime cost of production depending on the type of the carrying out of production, seriality, duration of the production process is ...
Гринько, Ю. В. +1 more
core
In situ hybridization and immunocytochemistry in serial sections of rabbit skeletal muscle to detect myosin expression. [PDF]
David J. Dix, Brenda R. Eisenberg
openalex +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source

