Results 141 to 150 of about 88,119 (330)
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Influence of Spinal Manipulative Therapy Force Magnitude and Application Site on Spinal Tissue Loading: A Biomechanical Robotic Serial Dissection Study in Porcine Motion Segments [PDF]
, 2017 Martha Funabashi +4 more
openalex +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
NTCP modeling and dose-volume correlations for acute xerostomia and dry eye after whole brain radiation. [PDF]
Radiat Oncol, 2021 Mavroidis P +10 more
europepmc +1 more source
Genomic expansion of Marek's disease virus DNA is associated with serial in vitro passage [PDF]
, 1985 R F Silva, R. L. Witter
openalex +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Contouring variation affects estimates of normal tissue complication probability for breast fibrosis after radiotherapy. [PDF]
Breast, 2023 Jaikuna T +24 more
europepmc +1 more source
UK Serials Group Serials Roadshow
Serials: The Journal for the Serials Community, 1994 In the July 1990 issue of Serials, Margaret Graham reported on an innovative programme of activity by the Group in some UK library schools-the Travelling Workshop. This article aims to bring members up to date on the current status of the programme.
openaire +2 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source