Artificial escape from XCI by DNA methylation editing of the CDKL5 gene. [PDF]
A significant number of X-linked genes escape from X chromosome inactivation and are associated with a distinct epigenetic signature. One epigenetic modification that strongly correlates with X-escape is reduced DNA methylation in promoter regions. Here,
Anderson, Johnathon D +14 more
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Free Scholarly Electronic Journals: How Good Are They?
Amidst the furor of serials price increases, there is a steadily growing segment of the serials landscape with prices that can't be beat, that is to say, free.
Michael Fosmire, Song Yu
doaj +1 more source
A Serial Study of Heart Function During Pregnancy, Lactation and the Dry Period in Dairy Goats Using Echocardiography [PDF]
Kjell Olsson +4 more
openalex +1 more source
Differential Pricing and Exchange Rate Profits [PDF]
Prior to 1993, Elsevier Science negotiated "spot rates" which were set sometime in the early summer and would depend on the value of the dollar relative to the European currencies on the day the currency futures were purchased. Futures would be purchased,
Roth, Dana L.
core
Drones: Innovative Technology for Use in Precision Pest Management. [PDF]
Arthropod pest outbreaks are unpredictable and not uniformly distributed within fields. Early outbreak detection and treatment application are inherent to effective pest management, allowing management decisions to be implemented before pests are well ...
de Lange, Elvira S +3 more
core +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Utility of serial urinary cytology in the initial evaluation of the patient with microscopic hematuria [PDF]
Kogenta Nakamura +6 more
openalex +1 more source
Attenuated African swine fever virus through serial passaging of viruses in cell culture: a brief review on the knowledge gathered during 60 years of research [PDF]
Xiaoyue Zhang +9 more
openalex +1 more source
An Early and Comprehensive Millimetre and Centimetre Wave and X-ray Study of SN 2011dh: a Non-Equipartition Blast Wave Expanding into a Massive Stellar Wind [PDF]
Only a handful of supernovae (SNe) have been studied in multiwavelengths from the radio to X-rays, starting a few days after the explosion. The early detection and classification of the nearby Type IIb SN 2011dh/PTF 11eon in M51 provides a unique ...
Arcavi, Iair +26 more
core +1 more source

