Results 121 to 130 of about 31,331 (306)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

СОВЕРШЕНСТВОВАНИЕ ПАРАМЕТРОВ СОВОКУПНОГО ФОНДА ПЕРИОДИКИ БИБЛИОТЕК НОВОСИБИРСКОГО НАУЧНОГО ЦЕНТРА СО РАН

open access: yesБиблиосфера, 2010
The results of the research work and practice of serials collection forming in the Central Library of the Siberian Branch of the Russian Academy of Sciences are presented.

doaj  

HELIN Serials Committee minutes for 9/22/98

open access: yes, 1998
Minutes of the Serials Committee of the HELIN Consortium for September ...
HELIN Consortium. Serials Committee
core  

Planning for the Budget-ocalypse: The Evolution of a Serials/ER Cancellation Methodology [PDF]

open access: yes, 2014
Presentation for the 2014 North American Serials Interest Group (NASIG) Annual Conference on the development of the University of North Texas (UNT)'s strategy for determining ...
Enoch, Todd, Harker, Karen
core  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

HELIN Serials Committee minutes for 10/09/03

open access: yes, 2003
Minutes of the Serials Committee of the HELIN Consortium for October ...
HELIN Consortium. Serials Committee
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

On Serial Correlation

open access: yesThe Annals of Mathematical Statistics, 1969
Define \begin{equation*}\tag{1.1}P = U/V \equiv \sum^m_{i=1}\lambda_ix_i^2/\sum^r_{i=1}x_i^2,\quad 1 \leqq m \leqq r,\end{equation*} where the $x_i$'s are independent and identically distributed as $N(0, 1)$, and $0 < \lambda_1 \leqq \lambda_2 \leqq \cdots \leqq \lambda_m$.
openaire   +2 more sources

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