Results 121 to 130 of about 59,528 (310)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

СОВЕРШЕНСТВОВАНИЕ ПАРАМЕТРОВ СОВОКУПНОГО ФОНДА ПЕРИОДИКИ БИБЛИОТЕК НОВОСИБИРСКОГО НАУЧНОГО ЦЕНТРА СО РАН

open access: yesБиблиосфера, 2010
The results of the research work and practice of serials collection forming in the Central Library of the Siberian Branch of the Russian Academy of Sciences are presented.

doaj  

An Early and Comprehensive Millimetre and Centimetre Wave and X-ray Study of SN 2011dh: a Non-Equipartition Blast Wave Expanding into a Massive Stellar Wind [PDF]

open access: yes, 2013
Only a handful of supernovae (SNe) have been studied in multiwavelengths from the radio to X-rays, starting a few days after the explosion. The early detection and classification of the nearby Type IIb SN 2011dh/PTF 11eon in M51 provides a unique ...
Arcavi, Iair   +26 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

National Library of Malaysia Annual Report 2001 [PDF]

open access: yes, 2001
This Annual Report reflects the PNM activities during 2001, to support their vision,"The National Library of Malaysia aspires to be a world class library in the provision of excellent information services towards the realization of Malaysia's vision of ...
Noor, Norpishah Mohd.
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

We Deserve Better: Spanish Adolescents’ Perspectives of the Portrayal of LGBTQ+ Characters in Fiction

open access: yesInternational Journal of Communication
This research explores Spanish adolescents’ attitudes toward the representation of young LGBTQ+ individuals in Spanish fiction series on digital platforms and TV channels.
María T. Soto-Sanfiel   +1 more
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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